放疗联合伊班磷酸钠治疗骨转移癌62例的对照研究  

Radiotherapy Combined with Ibandronate for Bone Metastasis:Control Study of 62 Cases

作　　者：李四新 易建莉 李尚富 吴群[2] 孙学雄[2] 

机构地区：[1]岳阳市二人民医院内科,湖南岳阳414000 [2]娄底市中心医院药剂科,湖南娄底417000

出　　处：《现代生物医学进展》2010年第13期2552-2554,2560,共4页Progress in Modern Biomedicine

基　　金：湖南省卫生厅科研课题(2007-B63)

摘　　要：目的:比较放疗联合伊班磷酸钠治疗与单纯应用放射治疗对骨转移癌的疗效。方法:将62例骨转移癌患者随机分成2组,分别给予放疗联合伊班磷酸钠(实验组)和放疗(对照组)进行治疗,疗程均为4个月,观察其疗效。结果:实验组和对照组的疗程结束后镇痛有效率分别为80.65%和90.32%,骨质修复情况更有效、生存质量有明显改善,两组间差别均有统计学意义(P<0.05)。结论:放疗联合伊班磷酸钠治疗骨转移癌比单纯放疗对骨转移癌临床疗效更满意,值得临床推广。Objective：To compare radiation curative effect of therapy combined with ibandronate treatment and single application of radiation therapy for bone metastases.Methods：62 patients with bone metastases were randomly divided into two groups,treated with radiotherapy combined with ibandronate（experimental group） and radiotherapy（control group） for treatment course of 4 months to evaluate efficacy.Results：The experimental group and control group after treatment effective analgesia were 80.65% and 90.32%;Bone repair is even more effective and significant improvement in quality of lifeexperimental group,It were statistically significant differences between the two groups（P〈0.05）.Conclusion：Radiotherapy combined with ibandronate treatment of bone metastases compared with radiotherapy alone on the clinical efficacy of bone metastases is more satisfactory and worthy of promotion.

关 键 词：伊班磷酸钠 放射治疗 骨转移癌 联合治疗 

分 类 号：R738.1[医药卫生—肿瘤]