角膜塑形镜治疗近视的临床观察和并发症分析  

Clinical observation and complications analysis of orthokeratology lens for myopia

作　　者：王跃静[1] 陈独娅[1] 成伟[1] 张传伟[1] 

机构地区：[1]江苏省中医院眼科,中国江苏省南京市210029

出　　处：《国际眼科杂志》2010年第8期1582-1584,共3页International Eye Science

摘　　要：目的:观察角膜塑形镜治疗近视的临床效果和并发症,并分析其相关因素。方法:选择由三个眼科中心提供的配戴角膜塑形镜的病历资料,患者共302例601眼,观察戴镜后1wk;1,3mo的裸眼视力、屈光状态、ORBSCAN检查、角膜荧光素染色裂隙灯显微镜检查的情况。所有观察病例的治疗前设为自身对照组。结果:戴镜后1wk;1,3mo的裸眼视力分别与戴镜前裸眼视力比,均有统计学意义(t=-95.920,-77.710,-65.362;P<0.01,<0.01,<0.01);戴镜后1wk;1,3mo的裸眼视力与戴镜前矫正视力1wk;1,3mo比,均无统计学意义(t=-1.364,0.599,0.581;P=0.174,0.550,0.562);戴镜后1wk;1,3mo的角膜前表面水平向曲率与戴镜前角膜前表面水平向曲率比,均有显著统计学意义(t=26.020,20.143,17.476;P<0.01,<0.01,<0.01);戴镜后1wk;1,3,6mo的角膜前表面垂直向曲率与戴镜前角膜前表面垂直向曲率比,均有显著统计学意义(t=22.505,20.626,21.667,25.397;P<0.01,<0.01,<0.01,<0.01);发生角膜上皮点状脱落和角膜中央明显压痕的病例在1wk时占7.5%,1mo时占6%,3mo占9.8%,其中反复出现角膜上皮点染和明显压痕的占2.5%。结论:角膜塑形镜治疗近视具有特有的降低近视度数速度快、效果显著、安全、可逆的优势,但矫正近视度有一定适用范围。·AIM：To observe the clinical effects and complications of orthokeratology lens for myopia,and to analyze the relevant factors.·METHODS：The medical records of orthokeratology lens wearer 302 cases 601 eyes from three eye centers were analyed and the uncorrected visual acuity,refractive status,Orbscan examination,fluorescein staining 1 week;1 month,3 months after wearing glasses were observed.The condition of all patients before treatment was regarded as control group.·RESULTS：There was significant difference 1 week;1 month,3 months after wearing glasses compared with before wearing glasses in uncorrected visual acuity（t=-95.920,-77.710,-65.362;P〈0.01,0.01,0.01）,the anterior corneal surface horizontal curvature（t=26.020,20.143,17.476;P〈0.01,0.01,0.01）and there was significant difference 1 week,1 month,3,6 months after wearing glasses compared with before wearing glasses in the anterior corneal surface perpendicular curvature（t=22.505,20.626,21.667,25.397;P〈0.01,〈0.01,〈0.01,〈0.01）;However,There were no significant difference in uncorrected visual acuity 1 week;1 month,3 months after wearing glasses compared with the corrected visual acuity before wearing glasses.（t=-1.364,0.599,0.581;P=0.174,0.550,0.562）;The punctate loss of corneal epithelium and indentation of center cornea appeared in 1 week was 7.5%,1 month 6%,3 months 9.8%,of which recurrence ratio was 2.5%.·CONCLUSION：Orthokeratology has the quick,effective,safe,and reversible advantages for myopia,whereas it has certain applicability for correction of myopia.

关 键 词：角膜塑形镜 治疗 近视 

分 类 号：R778[医药卫生—眼科]