稳定性同位素在兽药残留检测中的应用  

Application of Stable Isotope in Detection of Veterinary Drug Residues

作　　者：王伟[1] 刘占峰[1] 杜晓宁[1] 

机构地区：[1]上海化工研究院,上海200062

出　　处：《原子能科学技术》2010年第7期813-819,共7页Atomic Energy Science and Technology

基　　金：科技部"十一五"支撑计划资助项目(2006BAF07B03);国家质检总局科技专项资助项目(2009IK134)

摘　　要：近年来,国际上发生了一系列重大的食品安全事件,使得消费者对食品安全的信任度下降,对食品来源的关注逐渐增加。动物源性食品安全问题现已成为一全球性的议题。因此,建立一准确、灵敏、可靠的兽药残留分析方法刻不容缓。本文介绍了目前兽药残留分析的检测现状,概述了国内外利用同位素内标法测定兽药残留所达到的最低检测限,综述了稳定同位素标记化合物在抗生素类、呋喃药类和磺胺药类兽药残留检测中的应用研究进展,阐明了其应用对我国食品安全体系健康发展的重要意义。In recent years,there has happened a series of significant food safety events worldwide,which lower down consumers＇ confidence in food safety,and they are taking increasing care about the sources of their foods.The safety problem of animal-origin foods has become a global topic for discussion.Therefore,it is a pressing task to establish a precise,sensitive and reliable method for analyzing veterinary drug residue.An introduction of the present status regarding veterinary drug residue analysis was made in the paper,and it briefly summarized the limit of detection（LOD）and quantification（LOQ）which could be reached in veterinary drug residue analysis by isotopic internal standard method domestically and abroad.The paper also made a review of the progress in applied research of stable isotope labeled compound in veterinary drug residue analysis of,such as,antibiotic medicines,furans and sulfonamides.The paper elucidated the great importance of the application of stable isotopes in the sane development of China＇s food safety system.

关 键 词：稳定同位素 兽药残留 内标法 应用 

分 类 号：O628[理学—有机化学]