稽留流产绒毛组织人细小病毒B19、巨细胞病毒及弓形体感染的研究  

RELATIONSHIP BETWEEN INFECTIONS OF HUMAN PARVOVIRUS B19, CYTOMEGALOVIRUS, TOXOPLASMOSIS AND MISSED ABORTION

作　　者：钟梅[1] 温淑娟[1] 宋兰林[1] 彭彩娥[1] 

机构地区：[1]第一军医大学南方医院

出　　处：《解放军医学杂志》1999年第1期31-32,共2页Medical Journal of Chinese People's Liberation Army

基　　金：广东省自然科学基金

摘　　要：为研究细小病毒Ｂ１９、巨细胞病毒、弓形体与稽留流产的关系，应用聚合酶链反应技术（ＰＣＲ）检测稽留流产１０３例及人工流产５３例的绒毛组织中３种病原体ＤＮＡ。结果发现流产组细小病毒、巨细胞病毒、弓形体感染率分别为１７．４７％、２５．２４％、２９．１３％，明显高于对照组，流产组两种及两种以上的病原体感染者２０例，而对照组无多种病原体感染者。由此证明导致稽留流产可以一种病原体感染引起，也可能是多种病原体感染的后果。细小病毒Ｂ１９是引起稽留流产的主要病原体之一。To determine whether there is a relationship between infections of human Parvovirus B19, Cytomegalovirus, toxoplasmosis and missed abortion, embryo tissues from 103 cases of missed abortions of unknown cause were studied by using polymerase chain reaction (PCR) assay for 3 viruses. Fifty three fetal tissues were also examined as controls. The prevalence of Parvovirus B19 DNA, Cytomegalovirus, toxoplasmosis were 17.47%, 25.24%, 29.13% in the sera of abortion pregnant women, respectively. There was a significant difference in the control group. The results suggested that parvovirus B19 infection might be an important pathogen for missed abortion.

关 键 词：流产 稽留流产 绒毛组织 HPVB19 巨细胞病毒 

分 类 号：R714.210.2[医药卫生—妇产科学]