通心络胶囊对急性脑梗死患者血清铁蛋白和血液流变学的影响  

Effect of Tongxinluo Capsule on Serum Ferritin and Hemorheology in Patients with Acute Cerebral Infarction

作　　者：孔亮[1] 王挺刚[1] 邵小鹏[1] 桂树华[1] 顾俊泉[1] 

机构地区：[1]江苏省无锡市第三人民医院,无锡214041

出　　处：《实用中西医结合临床》2010年第4期6-7,共2页Practical Clinical Journal of Integrated Traditional Chinese and Western Medicine

摘　　要：目的:观察通心络胶囊对脑梗死患者的临床疗效及血清铁蛋白和血液流变学的影响。方法:将300例急性脑梗死患者随机分为治疗组(152例)和对照组(148例),治疗组予通心络胶囊和常规治疗,对照组予常规治疗,观察两组治疗前后血清铁蛋白和血液流变学的变化及治疗效果。结果:治疗组疗效优于对照组,差异有显著性(P<0.05);治疗组治疗后的全血黏度高切、全血黏度低切和血浆纤维蛋白原均较治疗前降低,差异有显著性(P<0.05);两组治疗后比较,治疗组血清铁蛋白低于对照组,差异有显著性(P<0.01),治疗组全血黏度高切、全血黏度低切和血浆纤维蛋白原低于对照组,差异有显著性(P<0.05)。结论:通心络胶囊能够降低急性脑梗死患者血清铁蛋白浓度,显著改善急性脑梗死患者血液流变学指标,提高临床治疗效果。Objective：To observe the effect of Tongxinluo capsule on serum ferritin and Hemorheology in acute cerebral infarction patients and investigate the clinical effect.Methods：300 Patients with cerebral infarction were randomly divided into treatment group（152 cases treated with Tongxinluo capsule and routine therapy） and control group（148 cases treated with routine therapy）,Oberservation were made on the changes of serum ferritin and hemorheology before and after treatment,so as to the clinical effect.Results：The clinical effect was significantly better in treatment group than that in control group（P0.05）,values of serum ferritin,tallcut viscosity,lowcut viscosity of whole blood and fibrinogen in theatment group were significantly lower than those before treatment（P0.01）,and those in theatment group were significantly lower than those in control group（P0.05）.Conclusion：Tongxinluo capsule could reduce the level of serum ferritin and improve the condition of hemorheology in acute cerebral infarction patients,it is an effective drug on cerebral infarction.

关 键 词：通心络胶囊 急性脑梗死 血清铁蛋白 血液流变学 

分 类 号：R743.33[医药卫生—神经病学与精神病学]