30岁以下妇科恶性肿瘤的临床分析  

An Analysis of Characteristics of Gynecological Malignancies in Young Women Aged Less than 30 Years

作　　者：张宇[1] 成娟[1] 谢秋如[1] 曾智[1] 

机构地区：[1]中山大学附属第三医院妇科,广州510630

出　　处：《中国临床实用医学》2010年第8期1-3,共3页China Clinical Practical Medicine

基　　金：广东省科技计划项目（项目编号：2009B030801121）

摘　　要：目的探讨30岁以下妇科恶性肿瘤的病例特征及合理的治疗措施。方法回顾性分析2000年1月至2009年12月间在我院住院诊治的30岁以下的妇科恶性肿瘤患者的临床资料，以及随访部分患者的月经生育情况等，进行统计分析总结。结果我院10年期间共收治妇科恶性肿瘤患者721例，30岁以下的患者56例，占7．77％，发生率排位分别为卵巢癌、恶性滋养细胞肿瘤、宫颈癌和子宫体恶性肿瘤。子宫体恶性肿瘤前5年收治数为0，后5年的收治数为3；宫颈癌收治比例从前5年的7．7％上升到后5年的23．3％，差异有统计学意义（P〈0．05）。30岁以下患者妇科恶性肿瘤的Ⅰ期诊断率分别为卵巢癌76．7％，宫体恶性肿瘤100％，恶性滋养细胞肿瘤35．7％，宫颈癌66．7％。14例卵巢癌患者行了保留生育功能的手术，12例恶性滋养细胞肿瘤只用化疗，1例宫颈原位癌患者行了宫颈锥切术。电话随访成功的10例卵巢恶性生殖细胞肿瘤患者，月经均基本正常，获得总妊娠数4例，其中3人各育1人；随访成功的9例恶性滋养细胞肿瘤患者中，月经均能恢复基本正常，共有2个妊娠，已出生一活胎；1例宫颈原位癌患者行了宫颈锥切术尚在随访1年中，无妊娠记录。结论30岁以下年轻女性的妇科恶性肿瘤发生率排位分别为卵巢癌、恶性滋养细胞肿瘤、宫颈癌和子宫体恶性肿瘤，而宫颈癌和子宫内膜癌的发病率有上升的趋势。各种保留生育功能或保留卵巢功能的治疗方法在不断地探讨总结中并形成规范。Objective To analysis the characteristics and optimal treatments of Gynecological malignancies in young women aged less than 30 years. Methods Retrospective analysis was performed for the clinical data of gynecological malignancies in young women aged less than 30 years who were treated in our hospital from January 2000 to December 2009, and a follow-up was made for the menstruation and fertility of the patients. Results 56 cases were identified from 721 cases of gynecological malignancies, including ovarian malignancies, choriocarcinoma malignancies, cervical cancer and uterus malignancies which were ranked in sequence. The most common ovarian malignancy was germ cell tumor. The case number of uterus malignancies was zero during the prior 5 years, and 3 during the latter 5 years. The case number of cervical cancer was 2 during the prior 5 years,and 7 during the latter 5 years. The rate of stage Ⅰ diagnosis were 76. 7% ,100% ,35.7%and 66. 7% for ovarian malignancies, uterus malignancies, choriocarcinoma malignancies and cervical cancer respectively. Conservative treatments for fertility were performed for 14 cases of ovarian malignancies, 12 cases of choriocarcinoma malignancies and 1 case of cervical cancer in situ. From the successful follow-up of 10 cases of ovarian ma- lignancies, all got near normal menstruation, total pregnancy number was 4 and 3 babies were got for 3 patients each. From the successful follow-up of 9 cases of choriocarcinoma malignancies, all got near normal menstrua- tion, total pregnancy number was 2 and 1 baby was got. And the case of cervical cancer in situ was followed up for 1 year after coin resection without pregnancy note. Conclusion Ovarian malignancies were the most common gynecological malignancies in young women aged less than 30 years,followed by choriocarcinoma malignancies, cervical cancer and uterus malignancies. And the incidence of cervical cancer and uterus malignancies were increasing. Many kinds of conservative methods for conserving young women s ovary function and

关 键 词：年轻女性 恶性肿瘤 诊治 

分 类 号：R737[医药卫生—肿瘤]