β-环糊精及其衍生物对维生素分子的识别作用  

Molecular Recognition of β-Cyclodextrin and Its Derivatives to Vitamins

作　　者：王茹林[1] 李寒青[1] 弓辉[1] 秦姝竹[1] 

机构地区：[1]山西医科大学化学教研室,山西太原030001

出　　处：《化学研究》2010年第4期55-57,共3页Chemical Research

基　　金：山西省科技厅自然科学基金资助项目(20051029)

摘　　要：以乙基紫(EV)为光谱探针,采用紫外-可见光谱法测定了两种维生素(V)与β-环糊精(β-CD)、羟丙基-β-环糊精(HP-β-CD)和磺丁醚-β-环糊精(SBE-β-CD)的包合特性.结果表明,多种弱相互作用力协同作用于环糊精的包合过程,主-客体间的尺寸匹配影响了包合物的稳定性.包合能力β-CD>HP-β-CD>SBE-β-CD.The inclusion interactions among two vitamins and β-cyclodextrin（β-CD）,hydroxypropyl-β-cyclodextrin（HP-β-CD）,and sulfobutylether-β-cyclodextrin（SBE-β-CD） were studied by means of ultraviolet-visible light spectrophotometry in the presence of ethyl violet as a spectral probe.Results show that several weak interactions cooperatively contribute to the inclusion complexation among vitamins and β-cyclodextrin plus its derivatives.The complex stability is dominated by the size/shape-matching between host and guest.The inclusion ability is ranked as β-CDHP-β-CDSBE-β-CD.

关 键 词：乙基紫 Β-环糊精 维生素 分子识别 

分 类 号：O629[理学—有机化学]