急性早幼粒细胞白血病46例临床分析  

Analysis of the curative effect in 46 cases of acute promyelocytic leukemia

作　　者：邱莹玉[1] 高凌霞[1] 刘翠英[1] 

机构地区：[1]河南省永城市人民医院血液科,河南永城476600

出　　处：《中国当代医药》2010年第22期20-21,共2页China Modern Medicine

摘　　要：目的:总结46例急性早幼粒细胞白血病(APL)的治疗、预后及不良反应,以达到提高缓解率,延长生存期的目的。方法:对46例APL患者治疗期间应用全反式维甲酸、亚砷酸、DA/MA/HA及复方黄黛片进行联合治疗。结果:本组46例APL患者除2例早期死亡外,其余44例均达到完全缓解(CR),CR率为95.7%。结论:应用全反式维甲酸、亚砷酸及复方黄黛片联合治疗APL是安全有效的,对初治或复发患者均具有疗效高、耐受性好的特点。Objective：To review the treatment,prognosis and adverse reaction in 46 cases of acute promyelocytic leukemia（APL）,leading to alleviation rate increased and lifetime prolonged.Methods：Treat 46 cases of APL patients with all-trans retinoic acid,arsenious acid,DA/MA/HA and compound Huangdai tablet.Results： 44 patients reached complete remission（CR）,except 2 cases of early death.CR rate was 95.7%.Conclusion：It is safe and effective with combination therapy of all-trans retinoic acid,arsenious acid and compound huangdai Tablet for APL patients.It has high efficacy and good tolerability for the first diagnosed and relapsed patients.

关 键 词：白血病 早幼粒细胞 急性 治疗结果 亚砷酸类 疗效分析 

分 类 号：R733.71[医药卫生—肿瘤]