GC/MS分析羰基化产物萘普生甲酯  

Gas Chromatography/Mass Spectrometry Analysis for Determination of Methylα-(6-Methoxyl-2-Naphthyl )Propionate from Carbonylation

作　　者：陈静[1] 周宏英[1] 李红兵[1] 杨效和[1] 杨军[1] 傅宏祥[1] 杨焱 

机构地区：[1]中国科学院兰州化学物理研究所,兰州730000 [2]甘肃省农业生产资料总公司商检科,兰州730000

出　　处：《色谱》1999年第2期221-222,共2页Chinese Journal of Chromatography

摘　　要：α－（6-甲氧基-2-萘基）-乙醇在催化剂的作用下，与甲醇和CO发生羰基化反应，一步生成α－（6-甲氧基-2-萘基）丙酸甲酯（萘晋生申酯）。应用气相色谱-质谱联用技术，对这个反应过程中生成的各种化合物进行了分析，获得两个中间产物6-甲氧基萘乙烯和1-甲氧基-1-（6'-甲氧基-2'-萘基）乙烷的GC／MS数据资料，为推测该催化反应机理提供了可靠的依据。a-(6-Methoxyl-2-naphthyl) ethanol can be carbonylated to form methyl-a-(6-methoxyl-2-naphthyl)propionate catalyzed by a catalyst in the pressnce of methanol. High efficiency capillary gas chromatography and GC/MS technique were used for determining products which were obtained from the carbonylation. An OV-101 fused silica capillary column (25 m ×0. 2 mm i. d. )and a flame ionization detector (FID)were employed in the GC analysis. The column temperature was kept at 250℃. Mass spectra were obtained by electron impact at 70 eV. The structures of four compounds were identified' The major product is methyla-(6-methoxy-2-naphthyl) propionate, and the two by-products are 2-vinyl-6-methoxynaphthalene and 1-methoxy- (6' -methoxy-2' -naphthyl ) ethanol.

关 键 词：萘普生甲酯 羰化反应 色质联用 

分 类 号：TQ463.4[化学工程—制药化工]