酶法测定血清总胆汁酸在肝病诊断中的应用  

Application of Enzymatic Method for the Measurement of Total Bile Acids in Serum for the Diagnosis of Liver Diseases

作　　者：王凤学[1] 李树仁[1] 

机构地区：[1]遵义医学院附属医院

出　　处：《贵州医药》1999年第2期82-84,共3页Guizhou Medical Journal

摘　　要：通过对英国ＲＡＮＤＯＸ公司生产的酶法测定总胆汁酸试剂盒临床应用应用的可行性进行评价和测定肝病患者血清ＴＢＡ含量，评价酶法测定血清ＴＢＡ在各种肝病诊断中的应用价值。结果；批内ｃｖ为１．２７％和０．８％，批间ｃｖ２．０９％和１．５０％，回收率为１０１．２％，线性范围０－３００μｍｏｌ／Ｌ。The enzymatic method for the measurement of total bile acids inserum was applicated to evaluate the clinical reliability and diagnosticvalue in liver diseases. The results showed that the total bile acidsconcentration leval in the acute icteric hepatitis group, acute anicterichepatitis group, chronic active hepatitis group, chronic persistent hep-atitis group, and cirrhosis of liver group were 184. 1± 136.8μmol/L (P < 0.001), 67.3 ± 47.9μmol/L (P < 0.001) ; 35.6 ± 14.35μmol/L (P< 0.001),9.5 ± 8.72 μmol/L (P >0.05) and 88.3 ±52.3μmol/L (P < 0. 001 ), respectively. The positive rate were100%, 90%,90%,0 and 100%, respectively. It suggessted that theenzymatic method for the measurement of total bile acids in serum isprecise and accurate. It will help to diagnose defferent types of hepaticdiseases by measuring total bile acids in serum.

关 键 词：胆汁酸 肝硬化 肝炎 诊断 测定 

分 类 号：R575.204[医药卫生—消化系统] R512.604[医药卫生—内科学]