引起消化性溃疡复发的危险因素分析及预防措施  

Recurrence of Peptic Ulcer Caused by Risk Factors and Preventive Measures

作　　者：张元湖 

机构地区：[1]江苏省邳州市东方医院消化内科,221300

出　　处：《中国医药指南》2010年第24期26-28,共3页Guide of China Medicine

摘　　要：目的探讨引起消化性溃疡复发的危险因素分析及预防措施。方法对2007年1月至2008年12月间邳州市东方医院诊治的经胃镜检查确诊是消化性溃疡患者愈合后通过门诊复诊、电话随访等,将胃镜复查确诊复发者设为观察组,按照1∶2比例选择未复发者作为对照组,比较两组患者在性别构成、年龄、不良生活方式、服NSAIDs、精神因素、复发季节、溃疡愈合质量等方面的差异。结果消化性溃疡患者220例,随访(14.5±4.6)个月;复发60例占27.3%,复发危险因素:男性、存在不良生活方式、服NSAIDs、精神因素、春秋季节,溃疡S1期愈合。结论消化性溃疡的复发与多种因素有关,应通过保持良好生活方式、心理行为干预、提高溃疡愈合质量、对于需长期服用NSAIDs时宜选用选择性COX-2抑制剂,应给予PPI预防性治疗来预防或减少复发。Objective Recurrence of peptic ulcer caused by risk factors and preventive measures. Method January 2007 to December 2008 diagnosis and treatment in Dongfang hospital is peptic ulcer diagnosed by endoscopy in patients with healed through the out-patient referral, telephone follow-up, will be reviewed gastroscopy confi rmed recurrence set to the observation group, according to 1∶2 proportional selection as a control group who did not relapse, compared two groups in gender composition, age, poor lifestyle, clothes NSAIDs, psychological factors, recurrence season, ulcer healing quality differences. Results Of peptic ulcer patients with 220 cases, follow-up of （14.5 ± 4.6） months; 60 cases of recurrence of 27.3%,Recurrence risk factors： male, there are unhealthy lifestyles, clothing NSAIDs, spiritual factors, spring and autumn, S1 ulcer healing. Conclusions The recurrence of peptic ulcer with a variety of factors, should be adopted to maintain a good lifestyle, psychological and behavioral interventions to improve the quality of ulcer healing, for when you need long-term use should use NSAIDs selective COX-2 inhibitors, PPI should be given to preventive treatment to prevent or reduce recurrence.

关 键 词：消化性溃疡 复发 危险因素 预防措施 

分 类 号：R573.1[医药卫生—消化系统]