急性脑梗死患者纤维蛋白原水平与颈动脉粥样硬化的相关性研究  

Fibrinogen levels in patients with acute cerebral infarction and carotid atherosclerosis study the correlation

作　　者：胡凡[1] 王卫真[2] 冯莉莉[2] 谢旭芳[1] 熊英琼[1] 张昆南[1] 

机构地区：[1]江西省人民医院神经内科,南昌330006 [2]江西省人民医院超声诊断科

出　　处：《中华脑血管病杂志（电子版）》2010年第4期3-5,共3页Chinese Journal of Cerebrovascular Diseases(Electronic Edition)

基　　金：十一五国家科技支撑计划资助项目(2008BAI68B03)

摘　　要：目的分析急性脑梗死患者的颈动脉硬化斑块的情况,了解血纤维蛋白原水平对颈动脉粥样硬化的影响。方法对我院2008年5月至2010年2月收治的126例急性脑梗死患者进行颈动脉彩色多普勒超声检查,记录颈动脉粥样硬化斑块的部位、大小、数目及颈动脉内膜中层厚度(intima-media thickness,IMT)。根据血纤维蛋白原水平将患者分为正常浓度组并对两组患者间颈动脉粥样硬化斑块特征进行分析比较分析。结果高浓度组患者双侧颈动脉斑块及IMT的发生率高于正常浓度组,两者差异显著。高浓度组患者的颈动脉IMT≥0.09mm的发生率高于正常浓度组,其差异亦具统计学显著性。结论作为卒中患者的重要危险因素之一,血纤维蛋白原水平与急性脑梗死患者颈动脉粥样硬化程度及颈动脉IMT密切相关。Objective carotid atherosclerosis in patients with acute cerebral infarction plaque situation, understanding the level of blood fibrinogen on carotid atherosclerosis effects. Methods From May 2008 to February 2010 126 patients with acute cerebral infarction treated patients with carotid artery color Doppler ultrasound recording of carotid atherosclerotic plaques in the location, size, number of carotid artery intima media thickness （intima-media thickness, IMT）. According to fibrinogen levels were divided into two groups of patients with normal concentrations and carotid artery between the characteristics of atherosclerotic plaque analysis and comparison analysis. Results in patients with high concentrations of plaques and bilateral carotid artery IMT was higher than normal concentration of the group, the difference was significant. Pa- tients with high levels of carotid artery IMT ≥ 0. 09 mm＇ s was higher than normal concentrations, the difference is statistically significant. Conclusion As an important stroke risk factor, blood fibrinogen levels and acute carotid artery atherosclerosis and carotid artery IMT is closely related to.

关 键 词：脑梗死 颈动脉粥样硬化斑块 纤维蛋白原 

分 类 号：R743.33[医药卫生—神经病学与精神病学]