多指标监测判断葡萄胎预后临床研究  

Multi- index Monitoring of the Prognosis for Hydatidiform Mole

作　　者：郝秋云[1] 唐乃富[1] 刘淑英[1] 颜淑霞[1] 

机构地区：[1]山东省济宁市第一人民医院

出　　处：《河南肿瘤学杂志》1999年第3期195-197,共3页Henan Journal of Oncology

摘　　要：目的判断葡萄胎患者的预后状况。方法观察葡萄胎患者刮宫后：①阴道流血及血HCG变化情况；②葡萄胎组织颗粒大小、子宫肌壁间有无浸润病灶及滋养细胞增生程度。结果发现葡萄胎患者二次刮宫后：①阴道不规则流血超过2周者，血HCG8周内仍未降至正常者；②葡萄组织以小葡萄为主、子宫肌壁间浸润病灶超过2周者，其恶变率明显增高。结论①观察患者血HCG水平及子宫肌壁间有无浸润病灶是首要监测手段。②对以小葡萄为主且二次刮宫后不规则阴道流血超过2周者应高度重视。③二次刮宫后血HCG8周内仍未降至正常、子宫肌壁间病灶持续存在，结合其临床表现，如伴有不规则阴道流血者应视其恶变。Objective To understand the prognosis of patients with hydatidiform mole .Methods After uterine curettage,vaginal hemorrhage and the change of HCG in the blood, the she of tissue pellets of hydatidiform mole,infiltra tion for parietal layer of the uterus, proliferation degree ot the trophocytes were observed in hydatidiform mole patients .Re sults The rate of canceration was incresed markedly in patients with the following conditions after secondary uterine curettage;①The time of inegular vaginal hemorrhage exceeded 2 weeks and HCG did not decline to nomal within 8 weeks; ②Small pellets accounted for overwhelming majority in hydatidiform mole tissues and teh of parietal layer infiltration ex ceeded 2 weeks. Conclusion ①Observing HCG and the inflitration foci between parietal layers is the chief monitoring measurement ②The patients with maximam small pellets and with vaginal hemorrhage exceeding 2 weeks after secondary terine curettage must by paid higher attention to.③Canceration can be diagnosed if HCG be not decline to normal within 8 week ther secondary uterine cutettage and the infiltration foci occur continuously, comvined with clinicalboon, e.g.irrgeular vaginal hemorrhage.[

关 键 词：葡萄胎 预后 多指标监测 

分 类 号：R737.330.7[医药卫生—肿瘤]