2,3—二氟—6—硝基苯酚的合成工艺  

A PROCESS STUDY ON SYNTHESIS OF2,3DIFLUORO6NITROPHENOL

作　　者：杨长生 蒋登高 

机构地区：郑州工业大学化工系

出　　处：《化学反应工程与工艺》1999年第2期129-132,共4页Chemical Reaction Engineering and Technology

摘　　要：研究了２，３，４－三氟硝基苯在碱性水溶液中制备２，３－二氟－６－硝基苯酚的新工艺，探讨了反应温度，碱量及浓度等对水解反应的影响，获得了２，３－二氟－６－硝基苯酚较佳的工艺条件，总收率≥８３％。A new process for hydrolysis of 2,3,4trifluoronitrobenzene to synthesize 2,3difluoro6nitrophenol in alkali solution was proposed. Mainfactors which affect the reactions, such as reaction temperature and charge ratio have been investigated. The optimum performance conditions ofreaction have been established. The total yield can reach to a value of greater than 83%.

关 键 词：二氟 硝基苯酚 水解 合成 工艺 制药 原料 

分 类 号：TQ246.14[化学工程—有机化工] TQ460.4