二维超声观察主动性心肺复苏对心室颤动犬心功能的影响  

Effects of active compression-decompression cardiopuimonary resuscitation on cardiac functions during ventricular fibrillation by two-dimensional echocardiography in dogs

作　　者：刘红臻[1] 钟敬泉[1] 孟祥林[1] 陶文[1] 张运[1] 

机构地区：[1]山东大学附属齐鲁医院心内科,济南250012

出　　处：《中华超声影像学杂志》2010年第8期708-710,共3页Chinese Journal of Ultrasonography

基　　金：基金项目：山东省科技攻关项目（2006GG2202004,2007GG30002005）

摘　　要：目的 探讨主动性心肺复苏对犬心室颤动（室颤）时心功能的影响.方法 应用经胸二维超声心动图分别测量犬室颤时主动性心肺复苏组（ACD-CPR组,12只）和标准心肺复苏组（S-CPR组,12只）左心室舒张末期容积、左心室收缩末期容积,计算左心室射血分数（LVEF）,比较两组间各项测量结果.结果 室颤时,两组左心室舒张末期容积较室颤前均有下降,但差异均无统计学意义（P＞0.05）;两组左心室收缩末期容积较室颤前显著增大,差异有统计学意义（P＜0.001）.CPR时,ACD-CPR组比S-CPR组左室舒张末期容积增加,但差异无统计学意义（P＞0.05）;前者比后者左室收缩末期容积减少,但差异无统计学意义（P＞0.05）.CPR时,ACD-CPR组与S-CPR组LVEF较室颤前显著下降,差异有统计学意义（P＜0.001）;前者LVEF较后者显著增加,差异有统计学意义（P=0.019）.结论 主动性心肺复苏较常规心肺复苏有助于改善左心室功能.Objective To compare the effect of active compression-decompression cardiopulmonary resuscitation（ACD-CPR） with standard- cardiopulmonary resuscitation（S-CPR） on ventricular function in a canine ventricular fibrillation model. Methods Ventricular fibrillation was induced in anesthetized and instrumented canine. Twenty-four dogs were randomly assigned to either ACD-CPR group or S-CPR group.After 4 minutes of untreated VF,two-dimension echocardiography was used to evaluate the left ventricular end-diastolic volume（LVEDV）,left ventricular end-systolic volume（LVESV） and left ventricular ejection fraction （LVEF） of every canine of the two groups when they were undergoing cardiopulmonary resuscitation. Results During ventricular fibrillation, both ACD-CPR group and S-CPR group showed decreased LVEDV compared with pre-ventricular fibrillation, but not statistically significant（ P 〉0.05）.LVEDV was increased in ACD-CPR group compared with S-CPR group, but not statistically significant （P〉 0. 05）. Both ACD-CPR group and S-CPR group showed significantly increased LVESV compared with pre-ventricular fibrillation,of which the difference was statistically significant （ P 〈0. 001）. Both ACD-CPRgroup and S-CPR group showed significantly decreased LVEF compared with pre-ventricular fibrillation,of which the difference was statistically significant （P 〈0. 001）. LVEF was increased in ACD-CPR group compared with S-CPR group,of which the difference was statistically significant （ P = 0.019）. Conclusions Compared with S-CPR,ACD-CPR resulted in higher LVEF.

关 键 词：超声心动描记术 心室颤动 心肺复苏 心室功能 左 

分 类 号：R541.75[医药卫生—心血管疾病]