炎症促发肿瘤转移的研究进展  

Research review about inflammation promoting neoplasm metastasis

作　　者：刘超(综述)[1] 黄源(综述)[1] 林进令(审校)[1] 

机构地区：[1]广西医科大学第一附属医院胃肠外科,南宁530021

出　　处：《国际肿瘤学杂志》2010年第6期422-425,共4页Journal of International Oncology

摘　　要：在肿瘤微环境中，炎症细胞通过释放相关炎症因子调控相应核转录因子介导的细胞内信号传递，致使上皮细胞向间质细胞转变，最终促使肿瘤转移。由于炎症与肿瘤转移的关系密切，或许通过了解肿瘤的生物特性和相关的炎症因素，为临床制定出相应的肿瘤治疗方案，进一步提高疗效有所裨益。In the tumor microenvironment, inflammatory cells regulate intracellular signaling transduction mediated by the corresponding nuclear transcription factor by releasing inflammatory factors,which leads to transformation of epithelial cells to mesenchymalcellsand eventually promote tumor metastasis. Because of the intimate relationship between inflammation and tumor metastasis , it would be helpful for further enhancement of effectiveness of tumor therapy if we could better understand both the biological character of tumor and the related inflammatory factors.

关 键 词：炎症 肿瘤转移 

分 类 号：R73-37[医药卫生—肿瘤]