乙型肝炎病毒感染模式特征分析  

Characteristic Analysis on Hepatitis B Virus(HBV) Infection Model

作　　者：范波[1] 王飞[1] 田茵[1] 陈建雄[1] 高莉敏[2] 

机构地区：[1]北京国际旅行卫生保健中心,北京100013 [2]北京中医药大学管理学院,北京100029

出　　处：《中国国境卫生检疫杂志》2010年第4期232-234,共3页Chinese Journal of Frontier Health and Quarantine

摘　　要：〔目的〕分析2006—2008年在北京国际旅行卫生保健中心体检的全部出境人员和部分社会体检人员乙型肝炎病毒(HBV)感染情况及乙型肝炎血清标志物的感染模式特征。〔方法〕用酶联免疫吸附试验(ELISA)测定乙型肝炎病毒五项血清标志物。〔结果〕在157627名体检人员中,乙型肝炎血清标志物有11种感染模式,一项或一项以上阳性者共18076例,感染率11.468%;其中31～40岁年龄段阳性者最多为4746例,阳性率为3.011%;全部阴性139551例,占总数的88.532%。HBsAg阳性有4种组合模式共3629人,检出率2.302%;HBsAb阳性有4种组合模式共4528例,检出率2.873%;HBeAg阳性有2种组合模式660例,检出率0.419%;HBeAb阳性有4种组合模式共5483例,检出率3.478%;HBcAb阳性有8种组合模式共14533例,检出率9.220%;小三阳2342例,检出率为1.486%;单纯HBcAb阳性者7112例,检出率为4.512%;单纯HBsAb阳性者3319例,检出率为2.106%。〔结论〕在北京国际旅行卫生保健中心体检人员中,乙肝感染率明显低于全国平均水平,乙肝血清标志物全部阴性者比例较高,提示加强这一群体的乙型肝炎免疫与检测工作十分重要。Objective To analyze the characteristics of hepatitis B virus（HBV） infection mode among exit personnel and some of the social medical staff from 2006 to 2008.Method The serum markers of hepatitis B virus was detected by Enzyme-linked immunosorbent assay（ELISA）.Result In 157 627 samples,there were 11 types of serum markers of HBV infection model.A total of 18 076 cases were positive in one or more indicators,the infection rate was 11.468%.In which,139 551 persons were negative,accounting for 88.532%.The largest number of positive group was 31～40 age group in which up to 4746 the positiue rate was 3.011%.3 629 cases were positive of HBsAg with four kinds of modes,the rate was 2.302%;4 528 cases were positive of HBsAg with four kinds of modes,the rate was 2.873%;660 cases were positive of HBeAg with two kinds of modes,the rate was 0.419%;5 483 cases were positive of HBeAb with four kinds of modes,the rate was 3.478%;1453 cases were positive of HBcAb with eight kinds of modes,the rate was 9.220%.The number of HBsAg（＋） HBeAb（＋） and HBcAb（＋） were 2 342 cases,the rate was 1.486%.The number of HBcAb（＋） was 7 112,the rate was 4.512%;Only HBsAb（＋） was 3 319,the rate was 2.106%.Conclusion The rate of HBV infection is significantly lower than the national average,all negative HBV serum markers had higher proportion,it is important to strengthen HBV immunization among exit groups.

关 键 词：体检人员 乙型肝炎病毒 感染模式 特征分析 

分 类 号：R155.5[医药卫生—营养与食品卫生学]