乳腺癌钼靶X线特征表现与C-erbB-2表达相关性的研究  

Correlation Between the Mammographic Features and the Expression of C-erbB-2 in Breast Carcinoma

作　　者：李青春[1] 姜浩[1] 陆瑶[2] 杨慧龄[1] 刘进才[1] 肖文连[1] 罗光华[1] 胡义燕[1] 

机构地区：[1]南华大学第一附属医院放射科,湖南衡阳421001 [2]南华大学第二附属医院放射科

出　　处：《南华大学学报（医学版）》2010年第5期624-627,共4页Journal of Nanhua University(Medical Edition)

摘　　要：目的研究乳腺癌钼靶X线特征表现与C-erbB-2表达的相关性。方法回顾分析91例术后病理诊断为乳腺癌患者的乳腺X线摄影胶片,按照ACR创立并推荐的BI-RADS,将X线所见分肿块(形状、边缘)、局限致密浸润影、恶性钙化进行描述,并与C-erbB-2表达进行对照,分析其相关性。结果乳腺癌恶性钙化灶与CerbB-2的表达有显著相关性(P<0.05)。结论乳腺癌钼靶X线特征表现与C-erbB-2表达有一定关联性,可初步判断C-erbB-2表达情况,并为判断肿瘤生物学行为及患者预后提供一定参考价值。Objective To investigate the correlation between the mammographic features of the breast carcinoma and the expression of C-erbB-2.Methods A retrospective study of 91 consecutive mammography patients with breast carcinomas was performed to determine the relationship between the mammographic features and the expression of C-erbB-2.Each patient was reviewed according to BI-RADS final assessment category system.The mammographic features were devided into mass（margin,shape）,local dense infiltratio,microcalcifications.Results The C-erbB-2 positive expression was correlated with microcalcifications in breast carcinoma（P0.05）. Conclusion the mammographic features of the breast carcinoma had a significant correlation with the expression of C-erbB-2.It is feasible to predict the expression of C-erbB-2 in breast carcinoma.So the biological behavior can be assessed by mammographic features,which provide information for prognosis.

关 键 词：乳腺癌 钼靶X线摄影 人类上皮生长因子2 

分 类 号：R730.44[医药卫生—肿瘤]