老年人重症肌无力临床研究  

Clinical study of myasthenia gravis in elderly patients

作　　者：王雅慧[1] 苏振丽[1] 

机构地区：[1]宝鸡市中心医院老年病科,陕西省宝鸡市721008

出　　处：《实用老年医学》2010年第4期297-299,共3页Practical Geriatrics

摘　　要：目的本文旨在探讨老年人重症肌无力(MG)的临床特点。方法将本院12年间诊治的458例MG,根据发病年龄分为小儿组(≤14岁)、成年组(15～59岁)及老年组(≥60岁)。回顾性分析各组病例的首发症状及其演变、合并症以及误诊情况,以明确老年MG患者的临床特点。结果老年组MG在整个MG人群中构成比小,男性发病者较多见,以延髓症状首发者多见,演变为呼吸困难者比例高,合并胸腺瘤者多而合并其他自体免疫病者少,以延髓症状首发而误诊为脑血管病者多见,病死率高,但死于肌无力危象者少,常死于多种并发症。结论掌握老年MG患者的临床特点有助于指导临床的诊断和治疗。Objective To study the clinical features of myasthenia gravis （MG） in elderly patients. Methods A total of 458 patients with MG were divided into three groups based on the onset age, which were juvenile group（≤14 years old）, adult group （15-59 years old） and aged group （≥60 years old）. The differences of the clinical manifestations among the groups were analyzed. Results There were more male patients than female （M∶F=1.48∶1） in the aged group. The major presentation symptom was bulbospinal symptoms in the aged group. The incidence of bulbospinal symptoms evolving to dyspnoea was high. The incidence of the complication of thymoma in elderly patients was high, while the incidence of other autoimmune diseases was low. The mortality was higher in the aged group. Most elderly patients died from various complication. Conclusions The elderly MG patients has unique clinical features, which might help diagnose and treat MG in clinic.

关 键 词：重症肌无力 老年人 临床研究 

分 类 号：R746.1[医药卫生—神经病学与精神病学]