终末期肝病模型对肝衰竭的近期预后价值  

The value of model end-stage liver disease score on predicting prognosis of acute liver failure

作　　者：刘志红[1] 江建宁[1] 罗光汉[1] 吴继周[1] 邓一鸣[1] 苏明华[1] 吴健林[1] 

机构地区：[1]广西医科大学第一附属医院,南宁市530021

出　　处：《中华实验和临床感染病杂志（电子版）》2010年第3期28-30,共3页Chinese Journal of Experimental and Clinical Infectious Diseases(Electronic Edition)

基　　金：广西自然科学基金桂科资助项目(0448055)

摘　　要：目的探讨终末期肝病模型(model for end-stage liver disease,MELD)评分系统对急性肝衰竭患者近期预后的价值。方法检测115例急性肝衰竭患者的肝、肾功能及凝血项,计算MELD评分,并随访90d的生存率,比较存活组与死亡组MELD分值,并观察分析不同预后患者入选后30d时MELD分值的动态变化。结果 115例急性肝衰竭患者中,死亡组基线MELD分值明显高于存活组,且基线MELD分值越高,病死率越高。死亡组入选后30d的MELD分值较基线MELD分值升高,存活组入选后30d的MELD分值较基线MELD分值下降。结论 MELD评分系统可以作为预测急性肝衰竭患者预后较客观的指标。纵向评估MELD分值的动态变化可以较客观地反映急性肝衰竭的进展。Objective To evaluate the significance of model end-stage liver disease （MELD） score in predicting the prognosis of acute liver failure. Methods The liver function, renal function, prothrombin time of all 115 patients with liver failure were detected, and corresponding MELD scores were calculated. The patients were graded according to MELD and the mortality in different grades were analyzed. Then the MELD scores of death group and survival group were compared. Results The MELD scores of patients in death group were higher than that in survival group. The scores of MELD had positive correlation with the actual mortality rate. The higher MELD score, the higher mortality rate. Conclusions The MELD score is valuable in predicting the prognosis of acute liver failure.

关 键 词：终末期肝病模型 MELD评分系统 肝衰竭 

分 类 号：R575.3[医药卫生—消化系统]