小剂量尿激酶联合依达拉奉治疗急性脑梗死临床观察  

Clinical observation of treatment of acute cerebral infarction for small doses of urokinase combined with edaravone

作　　者：杜巍[1] 刘继宁[1] 吕汝奇[1] 罗正海[1] 王英[1] 

机构地区：[1]四川省绵阳市中心医院急诊科,621000

出　　处：《内蒙古中医药》2010年第14期81-82,共2页Inner Mongolia Journal of Traditional Chinese Medicine

摘　　要：目的:探讨小剂量尿激酶联合依达拉奉治疗急性脑梗死的临床疗效。方法:选择2009年1月～2009年12月我院收治的急性脑梗死患者98例,随机将患者分为观察组和对照组,每组49例。两组患者均进行常规治疗,而观察组则在此基础上加用小剂量尿激酶与依达拉奉的联合治疗方案,并对两组患者的临床疗效等指标进行对比分析。结果:与对照组相比,观察组的基本治愈率和总有效率均明显提高,差别均具有统计学意义(P<0.05)。与此同时,观察组治疗后神经功能缺损评分明显降低,而治疗前后的评分差值则明显提高,差别均具有统计学意义(P<0.05)。结论:采用小剂量尿激酶联合依达拉奉治疗急性脑梗死,其疗效确切,效果显著,并且治疗过程中无明显的药物不良反应,是急性脑梗死患者较为理想的治疗方法。Objective： To probe into the clinical effect of treatment of acute cerebral infarction for small doses of urokinase combined with edaravone. Methods： Select March 2009 - December 2009 in our hospital in 98 patients with acute cerebral infarction, were randomly divided into two groups and the control group, 49 patients in each group. Routine treatment of patients in both groups, while the observation group on this basis with a small dose of urokinase with the combined edaravone treatment programs, and the two other indicators of clinical efficacy were compared. Restdts： Compared with control group, the patients of the basic cure rate and total effective rate were increased, but not significantly lower efficiency, there were significant differences （P〈0.05）. At the same time, the patients neurological deficit score after treatment significantly reduced the score difference before and after treatment were significantly higher, there were significant differences （P〈0.05）. Discussions： With small doses of urokinase combined with edaravone for acute cerebral infarction, its effects were positive, significant effect, and the course of treatment without significant adverse drug reactions in patients with acute cerebral infarction is an ideal treatment.

关 键 词：尿激酶 依达拉奉 急性脑梗死 

分 类 号：R743.33[医药卫生—神经病学与精神病学]