重症急性胰腺炎胃肠功能障碍的中西医结合治疗  

Integrated traditional Chinese medicine and Western medicine treatment of gastrointestinal dysmotility of severe acute panereatitis patients

作　　者：冯青青[1] 许永春[1] 李春安[1] 幸军[1] 樊拖迎[1] 

机构地区：[1]南昌市解放军第九四医院消化内科,江西330002

出　　处：《中华胰腺病杂志》2010年第4期248-250,共3页Chinese Journal of Pancreatology

基　　金：全军医药卫生科研基金资助（08MA064）

摘　　要：目的观察大黄灌胃、芒硝敷脐及静脉滴注复方丹参注射液对重症急性胰腺炎（SAP）并发胃肠功能障碍的治疗价值。方法将41例SAP患者按完全随机法分为常规组（20例）和中西医结合治疗（中西医）组（21例），中西医组在常规治疗的基础上给予大黄灌胃、芒硝敷脐及静脉滴注复方丹参注射液，观察两组患者胃肠功能恢复情况、并发症发生率及住院天数。结果中西医组患者腹胀缓解时间、首次排便时间及平均住院天数分别为（3．1±0．8）d、（3．1±0．8）d、（21．5±2．8）d，较常规组的（5．2±1．4）d、（4．7±1．3）d、（32．1±3．6）d均明显缩短（P〈0．05或P〈0．01）。中西医组发生并发症5例，较常规组的8例显著减少（P〈0．01）。中西医组病死1例，转手术1例，常规组病死1例，两组比较无显著差异（P〉0．05）。结论在常规治疗基础上联合大黄灌胃、芒硝敷脐及静脉滴注复方丹参注射液能有效促进SAP患者胃肠功能恢复，值得临床推广应用。Objective To investigate the effects of rhubarb and mirabilite and compound danshen injection on gastrointestinal dysmotility of severe acute pancreatitis （SAP）. Methods Forty-one SAP patients were randomly divided into two groups： Integration group （n = 21 ） were treated with rhubarb and mirabilite and compound danshen injection. Control group （ n = 20 ） were treated with conventional therapy. Recovery of gastrointestinal motility of two groups was observed, and the complication rate and hospital stay was recorded. Results The recovery of gastrointestinal motility, first defecation and hospital stay in integration group was （3.1±0.8）d, （3.1±0.8）d, （21.5 ±2.8 ）d, which were significantly shorter than those in control group [ （5.2±1.4） d, （4.7 ±1.3） d, （32.1 ±3.60） d, P 〈 0. 05 or P 〈 0.01. Five patients in integration group developed complication, which was significantly lower than 8 patients in control group （P 〈 0. 01 ） ]. One patient died and one patient received operation in integration group, and one patient died in control group, without significant difference between the two groups （P 〉 0.05 ）. Conclusions The combination of rhubarb and mirabilite and compound danshen injection in severe acute pancreatitis can promote the recovery of gastrointestinal motility.

关 键 词：胰腺炎 急性坏死性 胃肠道 功能恢复 中西医结合疗法 

分 类 号：R576[医药卫生—消化系统]