对非酒精性脂肪肝患者生活方式干预的效果评价  

Effectiveness of lifestyle intervention in non-alcoholic fatty liver disease

作　　者：章蓉[1,2] 吴凤芸[2] 徐贵发[1] 

机构地区：[1]山东大学公共卫生学院,济南250012 [2]青岛市市立医院超声科,山东青岛266071

出　　处：《山东大学学报（医学版）》2010年第8期113-116,共4页Journal of Shandong University:Health Sciences

摘　　要：目的评估生活方式干预对非酒精性脂肪肝患者的治疗效果。方法对105名非酒精性脂肪肝患者实施生活方式干预,包括健康教育、饮食干预与运动干预。根据超声诊断标准,将脂肪肝分为轻、中、重度3组,其中轻度组64人,中度组35人,重度组6人,并采用氯化酶法检测患者的血脂指标包括甘油三酯(TG)、总胆固醇(TC)、低密度脂蛋白(LDL)、高密度脂蛋白(HDL),12个月后复查超声及血脂指标,对其效果进行分析评估。结果干预后,轻度组中有40人消除脂肪肝(P<0.01);中度组中有28人转变成轻度脂肪肝,有3人消除脂肪肝(P<0.01);重度脂肪肝中有3人转变成中度脂肪肝(P<0.05);干预后TG、TC、LDL较干预前降低(P<0.05)。结论对非酒精性脂肪肝患者进行生活方式干预,可降低脂肪肝的发病率,提高脂肪肝的逆转率。Objective To evaluate therapeutic effectiveness of lifestyle intervention in non-alcoholic fatty liver disease.Methods 105 cases of non-alcoholic fatty liver patients were enrolled.Lifestyle interventions was applied to all of them,including learning knowledge of health,dietary control and exercises.There were 64 mild,35 moderate and 6 severe cases diagnosed by ultrasonic tomography.Triglyceride（TG）,total cholesterol（TC）,HDL-cholesterol（HDL） and LDL-cholesterol（LDL） were also measured.After 12 months of therapy,the effectiveness was evaluated.Results After 12-month lifestyle intervention,40 mild fatty liver patients recovered to normal（P0.01） while among moderate cases,28 turned into mild and 3 recovered to normal（P0.01）.3 severe cases became moderate（P0.05）.And TG、TC、LDL significantly decreased.Conclusion Lifestyle intervention can effectively reduce the morbidity rate and increase the recovery rate in non-alcoholic fatty liver patients.

关 键 词：非酒精性脂肪肝 生活方式 饮食干预 运动干预 

分 类 号：R575.5[医药卫生—消化系统]