稳定型含氯消毒剂消毒性能的研究  

RESEARCH ON THE DISINFECTION PROPERTIES OF STABLE CHLORINE-CONTAINING DISINFECTANT

作　　者：慈九正[1] 李长青[1] 包卫华[1] 彭国克[1] 肖潇[1] 仝国辉[1] 

机构地区：[1]北京市疾病预防控制中心,北京100013

出　　处：《中国消毒学杂志》2010年第5期524-526,529,共4页Chinese Journal of Disinfection

摘　　要：目的研究稳定型含氯消毒剂消毒效果及其有关性能。方法采用悬液定量、定性杀菌试验和动物试验方法,对该消毒剂的消毒相关性能进行了试验观察。结果该稳定型含氯消毒剂原液有效氯含量为63 g/L,经37℃存放90 d,有效氯含量下降率为9.05%。用含有效氯1 200 mg/L的该稳定型含氯消毒剂作用40 m in,对悬液内枯草杆菌黑色变种芽孢的平均杀灭对数值>5.00。含有效氯600 mg/L的消毒剂作用5 m in,对悬液内脊髓灰质炎病毒灭活对数值>4.00。含有效氯300 mg/L的该消毒剂作用2.5 m in,对悬液内大肠杆菌和金黄色葡萄球菌杀灭对数值均>5.00。该稳定型含氯消毒剂小鼠急性经口LD50>5 000 mg/kg(体重);对小鼠骨髓嗜多染红细胞微核试验结果阴性。含有效氯1 200 mg/L该消毒剂溶液对家兔一次完整皮肤刺激试验结果为无刺激性。结论该稳定型含氯消毒剂性能稳定,对悬液内病毒、细菌繁殖体和细菌芽孢杀灭效果较好,属于实际无毒级物质。Objective To study the disinfection efficacy and other properties of stable chlorine-containing disinfectant.Methods Suspension quantitative germicidal test,qualitative germicidal test and animal toxicity test were carried out to observe disinfection and other performance of this disinfectant.Results The concentration of available chlorine of this stable chlorine-containing disinfectant was 63 g/L and decreased about 9.05% after stored at 37℃ for 90 days.The average killing logarithm value of spores of Bacillus subtilis var.niger exposed to this disinfectant containing available chlorine 1 200 mg/L for 40 min was 5.00.The average killing logarithm value of Poliomyelitis virus exposed to this disinfectant containing available chlorine 600 mg/L for 5 min was 4.00.The average killing logarithm values of Escherichia coli and Staphylococcus aureus exposed to this disinfectant containing available chlorine 300 mg/L for 2.5 min was 5.00.The mouse acute oral toxicity LD50 of this disinfectant was5 000 mg/kg·bw.Mouse bone marrow polychromatic erythrocyte micronucleus test was negative.No irritation was found on the rabbit＇s skin in dermal irritation test of this disinfectant containing available chlorine 1 200 mg/L.Conclusion This stable chlorine-containing disinfectant has stable properties and good germicidal efficacy for virus,vegetative and spores of bacteria.It has no toxicity actually.

关 键 词：含氯消毒剂 稳定型 细菌芽孢 病毒 杀灭效果 

分 类 号：R187.2[医药卫生—流行病学]