2型糖尿病患者视网膜血管直径影响因素分析  

The influencing factors of retinal vessel caliber in type 2 diabetes mellitus

作　　者：郭倩茹[1] 徐应军[2] 

机构地区：[1]唐山工人医院分院唐山市铁路中心医院眼科,063003 [2]华北煤炭医学院科研处

出　　处：《中国医师进修杂志》2010年第25期28-31,共4页Chinese Journal of Postgraduates of Medicine

摘　　要：目的 探讨2型糖尿病患者视网膜微血管直径的影响因素,为进一步研究视网膜微血管直径的临床意义提供初步依据.方法 选取2型糖尿病患者200例,采用眼底彩色照相、计算机辅助测量视网膜血管直径,测定生化指标、血压,使用调查表询问一般资料,采用多元逐步回归分析视网膜微血管直径的影响因素.结果 视网膜静脉直径与年龄呈负相关（P〈0.01）,与空腹血糖、糖化血红蛋白、糖尿病病程呈正相关（P〈0.01）;视网膜动脉直径与年龄、血压、糖尿病病程均呈负相关（P〈0.01或〈0.05）.结论 2型糖尿病患者视网膜微血管直径受年龄、空腹血糖、糖化血红蛋白、血压、糖尿病病程的影响.Objective To study the influencing factors of retinal vessel caliber in type 2 diabetes mellitus and supply the elementary data for clinic. Methods Two hundred diabetic patients were involved in this study, and the vessel caliber was measured by fundus oculi color photo and computer-assisted imaging program. Biochemical indicator and blood pressure was examined and other document was achieved by questionaire. Results In type 2 diabetes mellitus, the retinal vein caliber had negative correlation with age and positive correlation with fasting blood glucose （FBG）, glycosylated hemoglobin A1c （HbA1c） and the duration of diabetes mellitus（P 〈 0.01 ）. The retinal arteriole caliber had negative correlation with age, blood pressure and the duration of diabetes mellitus （P 〈 0.01 or 〈 0.05 ）. Conclusion The influencing factors of retinal vessel caliber in type 2 diabetes mellitus are age,FBG,HbA1c,blood pressure and the duration of diabetes mellitus.

关 键 词：糖尿病 2型 视网膜血管 影响因素 

分 类 号：R774.1[医药卫生—眼科]