年轻妇女子宫颈癌的临床特征和预后分析  

Clinical features and prognosis of cervical cancer in young women

作　　者：曹兰琴[1] 黎欣[1] 张怡[1] 李新国[1] 王前[1] 

机构地区：[1]中南大学湘雅医院妇产科,长沙410008

出　　处：《中南大学学报（医学版）》2010年第8期875-878,共4页Journal of Central South University ：Medical Science

摘　　要：目的:探讨年轻妇女宫颈癌的发病趋势、病因、临床病理特征、治疗及预后等情况。方法:对132例年轻子宫颈癌患者的临床资料进行回顾性分析。结果:年轻宫颈癌患者中HPV18阳性率高;患者的临床表现主要为接触性阴道流血,宫颈肉眼观察以外生型为主;腺癌比例上升;治疗上以手术为主,在广泛性子宫切除术同时行卵巢移位术(鳞癌),术后无卵巢转移和更年期综合征的发生;术后大部分患者预后良好。结论:接触性阴道流血为年轻宫颈癌患者的主要症状;治疗上尽量采取手术,对局部晚期或中晚期的患者术前先进行新辅助化疗,术中可卵巢移位以保留卵巢功能。Objective To investigate the prevalence,etiology,clinical presentation and pathological features,treatment and prognosis of cervical cancer in young women.Methods Clinical data of 132 young women with cervical cancer were reviewed.Results Positive rate of human papillomavirus 18 was high in young women with cervical cancer.The primary clinical presentation of young patients with cervical cancer was contact bleeding of vagina,and the signs were out-expanding of cervical mass.The percentage of adenocarcinoma increased.The main treatment for cervical cancer was surgery.The patients had radical hysterectomy plus ovarian transplantation,none of whom had ovarian metastases and menopause syndrome.Prognosis of most patients was good.Conclusion Contact bleeding is a significant symptom in young women with cervical cancer.Surgery is first considered in the treatment.Preoperative neoadjuvant chemotherapy can be used in patients with locally advanced and late stage cervical cancer.Ovarian transplantation during operation can retain the ovary function.

关 键 词：子宫颈癌 年轻妇女 临床病理 治疗 

分 类 号：R737.33[医药卫生—肿瘤]