重型肝炎和活动性肝硬化并发医院感染的临床分析  

Nosocomial Infections in Severe Hepatitis and Active Hepatic Cirrhosis

作　　者：胡晓丽[1] 施中凯[2] 姜月红[2] 王竹[1] 赵宏伟[1] 

机构地区：[1]黑龙江省医院感染内科,哈尔滨150036 [2]黑龙江省医院检验科,哈尔滨150036

出　　处：《热带医学杂志》2010年第8期956-958,共3页Journal of Tropical Medicine

摘　　要：目的探讨重型肝炎及活动性肝硬化并发医院感染的病原菌、感染部位及临床耐药与疾病转归。方法对2006年1月至2009年10月住院的40例重型肝炎及活动性肝硬化患者合并感染培养阳性患者的病原菌进行回顾性研究。结果 304例患者并发医院感染者40例,感染率为13.16%。细菌感染者以革兰氏阴性杆菌为主,主要感染部位为呼吸道,真菌感染者以白色念珠菌为主。结论本院重型肝炎及肝硬化并发医院感染的主要危险因素与肝脏储备功能下降、有创性操作及预防性应用抗生素有关。Objective To investigate the pathogenic bacteria,site of infection,drug resistance and clinical outcome in severe hepatitis and hepatic cirrhosis with nosocomial infection.Method We reviewed the severe hepatitis and hepatic cirrhosis cases admitted to our hospital between January 2006 to October 2009,who were infected with the pathogenic bacteria and whose specimen culture were positive.Results 40 patients were found with nosocomial infection in 304 patients,with the infection rate of 13.16%.Bacterial infection is mainly Gram-negative bacteria and the main site of infection was respiratory tract.Fungal infection is mainly Candida albicans.Conclusion The risk factors of hospital infection in patients with severe liver diseases in our hospital have relationship with decreased liver reserve faction,invasive operation and preventive application of antibiotics.

关 键 词：重型肝炎 肝炎肝硬化 医院感染 

分 类 号：R575.2[医药卫生—消化系统]