保乳术综合三维适形放疗治疗Ⅰ期乳腺癌的临床观察  

Clinical effects of breast-conserving combining with three-dimensional conformal radiotherapy （3D CRT） for stage I breast cancer

作　　者：张纯[1] 赵艳海[1] 张雪芳[1] 吴伟艺[1] 吴煜良[1] 莫杰明[1] 

机构地区：[1]广东省东莞市人民医院放疗科,523018

出　　处：《中国临床实用医学》2010年第9期73-75,共3页China Clinical Practical Medicine

摘　　要：目的观察Ⅰ期乳腺癌保乳术后三维适形放疗疗效及副作用。方法30例确诊Ⅰ期乳腺癌患者保乳术后进行三维适形放疗。照射靶区为患侧全乳及胸壁和腋窝锁骨上区。全乳及胸壁采用半野切线对穿照射，90％门VD，50Gy／25次／5周，靶区内剂量分布±5．0％，患侧肺V20〈20％。瘤床野以术痕外扩3．0cm，避开乳头，银夹的位置为瘤床深度，5mm等效膜填充，6MeV电子线追加照射，DT10Gy／5次／1周。患侧腋窝锁骨上区6MV—X照射Dr50Gy／25次／5周。结果随访5年未见局部复发。美容效果“优”和“好”100％。近期毒副反应可耐受。结论早期乳腺癌保乳术加术后三维适形放疗局部控制率及美容效果满意，无严重并发症。Objective To observe the curative effects and side reactions of patients suffer from stage I breast cancer after breast-conserving combining with three-dimensional conformal radiotherapy （3D CRT）. Methods Thirty clinical stage I breast cancer patients received 3D CRT after breast-conserving therapy. A dose of 50 Gy with 6-MV X-rays was prescribed to the target volume consisting of the involved breast, chest wall, supraclavicular,and axillary nodes. And added 10 Gy to the tumor bed with 6-MeV electrons. Results The follow-up time was five years. No patients recurred. All patients obtained excellent cosmetic result. And the short term side reactions is acceptable. Conclusion Three-dimensional conformal radiotherapy combined with breastconserving therapy can well achieve ideal local control rate and cosmetic outcome for earlier breast cancer. And no serious complication is observed.

关 键 词：乳腺肿瘤 放射治疗 手术疗法 综合治疗 美容效果 

分 类 号：R737.9[医药卫生—肿瘤]