氯霉素滴眼液中可见异物检查的探索性研究  

Exploratory Study on Visible Particles Inspection of Chloramphenicol Ophthalmic Solution

作　　者：易大为[1] 刘杨[1] 仲瑶[1] 

机构地区：[1]辽宁省食品药品检验所,辽宁沈阳110023

出　　处：《食品与药品》2010年第9期339-341,共3页Food and Drug

摘　　要：目的研究氯霉素滴眼液中可见异物的成因。方法运用因果关系分析法和相关性分析法,研究引入可见异物的关联因素,通过微生物试验求证可见异物与微生物污染的相关性。结果可见异物不合格的样品中,66.7%的批次存在霉菌污染。结论氯霉素滴眼液中可见异物与微生物污染有相关性。Objective To study the source of visible particles in chloramphenicol ophthalmic solution.Methods The associated factors which triggers the visible particles were investigated by the cause-effect relationship analysis and correlation analysis.The correlation between visible particles and microbial contamination was verified by the microbiological test.Results The mold contamination rate was 66.7 % in the batches with visible particles exceeding the limit.Conclusion There is a correlation between visible particles and microbial contamination in chloramphenicol ophthalmic solution.

关 键 词：氯霉素滴眼液 可见异物 霉菌污染 

分 类 号：R988.1[医药卫生—药品]