对叔丁基苯甲醛的合成  

Synthesis of 4-tert-butyl-benzaldehyde

作　　者：王帅军[1] 顾强[1] 陈晓东[2] 赵天琦[1] 赵楠[1] 张玉敏[1] 

机构地区：[1]吉林大学化学学院 [2]吉林大学测试科学实验中心,吉林长春130021

出　　处：《化学试剂》2010年第9期835-839,共5页Chemical Reagents

摘　　要：以对叔丁基甲苯为原料,分别采用Mn2O3、MnO2氧化法,苄溴水解法,索默勒(sommelet)法和2-碘酰基苯甲酸(IBX)氧化法合成了标题化合物。主要考察了各影响因素对MnO2氧化生成对叔丁基苯甲醛产率的影响,确定了最佳合成工艺。同时探究了其他方法合成对叔丁基苯甲醛的可能性,其中以IBX氧化法获得的产率最高,可达86%。4-tert-Butyl-benzaldehyde was synthesized from 4-tert-butyl toluene via oxidation by Mn2O3 and MnO2,benzyl halide hydrolysis,the Sommelet reaction and oxidation of IBX,respectively.The influence of various factors on formation of 4-tert-butyl-benzaldehyde by oxidation in the presence of MnO2 was predominantly studied.The optimum synthetic conditions were determined,while other methods for synthesizing 4-tert-butyl-benzaldehyde were also explored,among which the IBX oxidation method could lead to a highest product yield of 86%.

关 键 词：对叔丁基苯甲醛 对叔丁基甲苯 合成 

分 类 号：O625.41[理学—有机化学]