碳酸乙烯酯法合成N-芳基-2-噁唑烷酮  

Synthesis of N-aryl-2-oxazolidinone derivatives from ethylene carbonate

作　　者：杨超[1] 刘毅锋[1] 张娟[1] 尚卫东[1] 

机构地区：[1]西北大学应用化学研究所,陕西西安710069

出　　处：《化学试剂》2010年第9期847-850,共4页Chemical Reagents

摘　　要：以纳米ZnO为催化剂,通过尿素的乙二醇醇解反应合成碳酸乙烯酯,实验表明:在常压下,尿素与干燥的乙二醇比例为1∶1,150℃反应8h,碳酸乙烯酯的产率为90.9%。再以碳酸乙烯酯和芳胺为原料,在Na-Y分子筛和K2CO3催化下,DMF为溶剂,回流反应3h,合成标题化合物,产率50%～85%,并利用元素分析、1HNMR、13CNMR、IR对目标化合物进行了表征。Ethylene carbonate（EC）was synthesized via the alcoholysis reaction of urea with ethylene glycol in the presence of nano ZnO catalysts.It was demonstrated that 90.9% of EC yield could be reached at 150 ℃ during alcoholysis of urea with EG for 8 hours under atmospheric pressure,with the most appropriate mole ratio of urea/EG equating to 1.0.Using Na-Y zeolite and K2CO3 as the catalysts,N-aryl-2-oxazolidinone derivatives were synthesized by the reaction of aryl amine and ethylene carbonate in DMF under refluxing for 3 h to achieve a product yield of 50%～85%.The structures of target compounds were identified by elemental analy-sis,1HNMR,13CNMR and IR spectroscopies.

关 键 词：纳米氧化锌 碳酸乙烯酯 芳胺 合成 N-芳基取代噁唑烷酮 

分 类 号：O626.2[理学—有机化学]