晚香玉香精壳聚糖纳米粒的制备及表征  

Preparation and Characterization of Tuberose Fragrance-Loaded Chitosan Nanoparticles

作　　者：王明熙[1,2] 肖作兵[1] 胡静[1] 周如隽[1,2] 黄丽丽[1] 

机构地区：[1]上海应用技术学院香料香精技术与工程学院,上海200235 [2]上海海洋大学食品学院,上海201306

出　　处：《精细化工》2010年第9期874-878,共5页Fine Chemicals

基　　金：国家基础研究发展规划(973计划)项目(2009CB226104);国家自然科学基金项目(20876097);上海市纳米专项资助项目(0952nm06100)~~

摘　　要：以三聚磷酸钠(TPP)为交联剂,通过离子凝胶法制备晚香玉香精壳聚糖纳米粒。研究了壳聚糖质量浓度、香精质量浓度、乳化剂与香精的质量比及反应时间对晚香玉香精壳聚糖纳米粒粒径的影响,并采用动态激光光散射仪(DLS)、透射电镜(TEM)、红外光谱仪(IR)及热重分析仪(TGA)对其结构及性能进行了表征。结果表明,当壳聚糖质量浓度为1.71 g/L、香精质量浓度为1.72 g/L、m(乳化剂)∶m(香精)=1∶2、反应时间为1 h时,制备的晚香玉香精壳聚糖纳米粒平均粒径为138 nm,粒径分布系数为0.100,香精装载量达28.4%,能减缓高温下香精的释放速率。On the base of using sodium tripolyphosphate（TPP） as a crosslinker,tuberose fragrance-loaded chitosan nanoparticles were prepared by the ionic gelation method.The effects of the mass concentration of chitosan,the mass concentration of tuberose fragrance,the mass ratio between emulsifier and fragrance and the reaction time to the size distribution of tuberose fragrance-loaded chitosan nanoparticles were investigated.The tuberose fragrance-loaded chitosan nanoparticles were characterized by dynamic light scattering（DLS）,transmission electron microscopy（TEM）,infrared spectroscopy（IR） and thermogravimetric analysis（TGA）.Results showed that the average particle size was 138 nm,the polydispersity was 0.100 and the fragrance loading capacity was 28.4% when the chitosan mass concentration was 1.71 g/L,the fragrance mass concentration was 1.72 g/L,m（emulsifier）∶m（fragrance）=1∶2 and reaction time was 1 h.Under the high temperature,the release rate of tuberose fragrance loaded by chitosan nanoparticles was decreased.

关 键 词：壳聚糖 离子凝胶 纳米粒 晚香玉香精 

分 类 号：TQ657[化学工程—精细化工] O636.1[理学—高分子化学]