牛血小板衍化生长因子盖髓的实验研究  

Experimental study on bovine platelet-derived growth factor as a pulp capping material

作　　者：李国华[1,2] 朱南洲[1,2] 刘忠 李芸[1,2] 金岩 陈强[1,2] 

机构地区：[1]解放军210医院 [2]第四军医大学口腔医学院

出　　处：《牙体牙髓牙周病学杂志》1999年第2期117-119,共3页Chinese Journal of Conservative Dentistry

摘　　要：目的：观察牛血小板衍化生长因子（ｂＰＤＧＦ）覆盖狗暴露牙髓后的盖髓效果。方法：用活体狗牙作直接盖髓实验，并用组织学方法评价其效果。结果：术后６周，ｂＰＤＧＦ能够诱导牙髓成纤维细胞、内皮细胞增殖及抑制炎症反应，提高牙髓修复能力。结论：ｂＰＤＧＦ促进狗牙髓组织修复。Aim: To observe the effects of bovine platelet derived growth factor(bPDGF) on the exposed dog pulp. Methods: The results were evaluated histopathologically. Results: Six weeks postoperatively, bPDGF was able to induce the proliferation of the pulp cells (fibroblasts) and endothelial cells, to inhibit the inflammatory reaction of pulp, and to enhance the pulp repairing. Conclusion: bPDGF promotes the repair of dog pulp tissues.

关 键 词：盖髓 血小板 衍化生长因子 牙髓病 

分 类 号：R781.305[医药卫生—口腔医学]