急性脑血管病患者血清超敏C反应蛋白水平变化及意义  

The relationship between highly sensitive C-reactive protein and acute cerebrovascular disease

作　　者：张慧[1] 渠华[1] 卞超[1] 

机构地区：[1]兖矿集团总医院检验科,山东省邹城273500

出　　处：《中国基层医药》2010年第16期2195-2196,共2页Chinese Journal of Primary Medicine and Pharmacy

摘　　要：目的 观察急性脑血管病患者血清超敏C反应蛋白（hs-CRP）水平变化及其临床意义. 方法 通过检测60例急性脑梗死患者（脑梗死组）、60例脑出血患者（脑出血组）和40名健康体检者（对照组）血清hs-CRP水平,比较三组血清hs-CRP水平变化情况. 结果 脑梗死组和脑出血组血清hs-CRP水平明显高于对照组（t=19.712、13.217,均P＜0.01）,脑梗死组与脑出血组hs-CRP水平差异无统计学意义（P＞0.05）. 结论 血清hs-CRP水平增高与脑血管病的发生有密切关系.Objective To investigate the changes of the serum level of highly sensitive C-reactive protein （hs-CRP）in patients with cerebrovascular disease and its clinical significance. Methods The serum level of hs-CRP in 60 patients with acute cerebral infarction and 60 patients with acute cerebral hemorrhage and 40 healthy persons were determined.All the patients were scored by clinic neurological deficit scale（NDS）,and were compared in groups. Results The serum level of hs-CRP in patients with acute cerebral infarction and with acute cerebral hemorrhage were significantly higher than that in normal controls（t=19.712 13.217 P 〈0.01）.There was no obvious difference between the patients with acute cerebral infarction and with acute cerebral hemorrhage. Conclusion The serum level of hs-CRP was closely correlated with the severity of cerebrovascular disease.

关 键 词：动脉粥样硬化 脑血管意外脑出血 C反应蛋白质 

分 类 号：R74[医药卫生—神经病学与精神病学]