彩色多普勒超声对绝经期宫颈癌放疗后血流改变的研究  

Effects of Radiotherapy on Uterine Blood Flow in Patients with Postmenopausal Cervical Carcinoma Studied by Color Doppler Ultrasonography

作　　者：黄建国[1] 王章容[1] 

机构地区：[1]武汉市湖北省肿瘤医院超声波室

出　　处：《中国超声医学杂志》1999年第4期297-299,共3页Chinese Journal of Ultrasound in Medicine

摘　　要：目的：评价放疗所致宫颈癌血流的改变及其临床意义。方法：对４９例绝经后宫颈癌患者在放疗前后进行了彩色多普勒观测。肿瘤放疗量３６～７０Ｇｙ。结果：放疗导致子宫动脉血流速度降低，其中５１％（２５／４９）的病例未检测到子宫动脉的流速，４１％（２０／４９）的病例子宫动脉流速＜１０ｃｍ／ｓ。可检测到子宫动脉血流的２４例中ＲＩ＞０．６占８３％（２０／２４）。放疗中子宫动脉血流速度降低，ＲＩ增大，肿瘤内血管减少是预后良好的表现。相反，放疗后仍可见过多的血管则需进一步治疗。结论：ＣＤＦＩ能有效地早期评价宫颈癌在放疗中肿瘤血管对放疗的反应，从而有助于及时调整治疗方案，使其获得更好的疗效。Objective:To evaluate radiotherapy induced tumor blood flow changes by color Doppler ultrasonography and its clinical significance.Methods:Color Doppler examination was performed on 49 patients with postmenopausal cervical carcinoma treated with radiotherapy.The radiation doses varied from 36 Gy to 70Gy.Results:Radiotherapy caused decrease in the peak systolic blood flow velocity of uterine artery.The uterine artery was not detected by color Doppler ultrasound in 51%(25/49).The RI values of the uterine artery>0 6 held 83% (20/24).The decrease of intratumoral vascularity and reduction of blood flow velocity of uterine artery with increased RI during the radiotherapy were associated with better results.however,persistence of excessive vascularity at the end of radiotherapy needed further treatment.Conclusion:These results suggested that color Doppler ultrasonography might be useful in early assessment of vascular therapeutic response of radiotherapy.Modifying the treatment schedules according to early therapeutic response help achieve better outcome.

关 键 词：宫颈癌 彩色多普勒超声 放射疗法 血流改变 

分 类 号：R737.330.5[医药卫生—肿瘤] R730.41[医药卫生—临床医学]