原发性肺癌患者治疗前后放射性核素骨显像的应用价值  

Application value of radionuclide bone imaging in patients with primary pulmonary cancer before and after treatment

作　　者：吴志兴[1] 吕宽[1] 李尚滨[1] 

机构地区：[1]山东大学附属省立医院核医学科,济南250021

出　　处：《国际肿瘤学杂志》2010年第8期630-632,共3页Journal of International Oncology

摘　　要：目的 探讨核素骨显像在原发性肺癌患者治疗前帮助确定治疗方案及治疗后定期随访的应用价值.方法 对810例原发性肺癌患者在治疗前进行了核素骨显像,对其中采用手术治疗的492例患者术后2年进行了核素骨显像随访,非手术治疗的318例患者中,治疗前无骨转移的142例患者治疗后进行了2年的核素骨显像随访.结果 在810例肺癌患者治疗前共检出骨转移179例,占22.1%,其中多发性骨转移157例,单发性骨转移22例,骨转移灶绝大多数分布于胸部、脊柱及骨盆.手术后2年内检出骨转移57例.非手术治疗且治疗前无骨转移的142例患者在2年内新检出骨转移患者79例.结论核素骨显像在肺癌治疗前可帮助疾病分期及确定治疗方案.手术治疗后定期骨显像有助于早期发现骨转移及确定相应治疗方案,应作为检查骨转移的首选方法.其他方法治疗后骨显像随访,可能有助于对患者预后的判断.Objective To probe the application value of radionuclide bone imaging in pre-treatment selection of therapeutic plan and regular post-treatment follow-up of patients with primary pulmonary cancer.Methods 810 patients with primary pulmonary cancer had radionuclide bone imaging respectively before the treatment. The follow-up radionuclide bone imaging was performed in 492 cases that were treated by surgery in 2 years after the operation. For 318 cases that were treated by non-surgery way,only 142 cases that had no skeletal metastases had follow-up radionuclide bone imaging in 2 years after the treatment. Results 179 cases （22.1%） had skeletal metastases in 810 cases. Multiple skeletal lesions were found in 157 cases and single skeletal lesion found in 22 cases. The majority sites of skeletal metastases were ribs, vertebrae column and pelvis. 57 cases that were treated by surgery had new skeletal lesions in 2 years after the operation. For non-surgery patients,79 cases had new skeletal lesions in 2 years after the treatment. Conclusion Radionuclide bone imaging is useful in the selection of therapeutic plan and staging of primary pulmonary cancer before the treatment.Regular bone imaging after the operation is helpful to detect early bone metastasis and choose the therapeutic plan, and should be regarded as a foremost method to detect the skeletal lesion. Radionuclide bone imaging after the non-surgery treatment maybe help us to conclude the prognosis of the patients.

关 键 词：肺肿瘤 肿瘤转移 骨 放射性核素显像 

分 类 号：R734.2[医药卫生—肿瘤]