宫颈上皮内瘤样病变135例三年随访分析  

Analysis of diagnosis and follow-up results in 135 CIN patients

作　　者：石云[1] 王晓莉[2] 刘朝晖[1] 

机构地区：[1]北京大学第一医院妇产科,100034 [2]中国疾病预防控制中心病毒病预防控制所

出　　处：《中华实验和临床病毒学杂志》2010年第4期245-247,共3页Chinese Journal of Experimental and Clinical Virology

摘　　要：目的 探讨宫颈薄层细胞学检查（TCT）和HPV检测联合筛查在宫颈上皮内瘤样病变（CIN）诊治和随访中的作用.方法 对2006年进行细胞学检查异常,且组织病理学诊断为宫颈上皮内瘤样病变的患者共135人进行病例回顾性总结,并在2006年至2009年进行连续随访,对其进行TCT和HPV检测.结果 （1）73例高危型HPV阳性的患者中,15例为ASCUS,3例为ASCUS-H,28例为LSIL,27例为HSIL;17例为CINⅠ,24例为CINⅡ,30例为CINⅢ,2例为CINⅢ可疑早侵.（2）3次随访中未出现CIN复发或病理升级情况.结论 HPV检测联合宫颈细胞学检查法在宫颈上皮内瘤样病变的诊治和随访中具有重要的意义.Objective To investigate the value of TCT and HPV detect in CIN patients. Method 135 patients diagnosed as CIN by pathologic method were involved. Their clinical and pathological data were reviewed and were given a 3-times follow-up in 2007,2008 and 2009. The follow-up studies include TCT and HPV detect. Results （1） in 73 HR-HPV positive patients, 15 of them were diagnosed as ASCUS, 3 were ASCUS-H ,28 were LSIL and 27 were HSIL by ThinPrep Cytology Test（TCT）. In those 73 patients, 17 of them were CIN Ⅰ,24 were CIN Ⅱ,30 were CIN Ⅲ and 2 were possibly-invasive cervical cancer. （2） in the 3-times follow-up, non of the patients recurred. Conclusion TCT and HPV detect are effective in diagnose and follow-up of CIN patient.

关 键 词：细胞学 乳头状瘤病毒 人 宫颈上皮内瘤样病变 

分 类 号：R737.33[医药卫生—肿瘤]