调强放疗联合化疗治疗复发性鼻咽癌30例临床研究  

Clinical study of cocurrent chemoradiotherapy with intensity modulated radiotherapy(IMRT) in 30 patiens of relapse Nasopharyngeal carcinoma

作　　者：李高峰[1] 宁四海[1] 李桂生[1] 黄健[1] 

机构地区：[1]广西柳州市工人医院肿瘤科,广西柳州545005

出　　处：《现代肿瘤医学》2010年第9期1719-1720,共2页Journal of Modern Oncology

基　　金：广西卫生厅基金资助(Z2009369);柳州市科技局基金资助(2009021509)

摘　　要：目的:探讨调强放疗联合化疗治疗复发性鼻咽癌的疗效。方法:30例复发性鼻咽癌患者给予调强放疗,同时联合化疗,观察疗效及不良反应。结果:CR53.33%(16/30),PR23.33%(7/30),NC23.33%(7/30)。1年生存率为93.33%(28/30),局部控制率为83.33%(25/30),远处转移率为18.5%,出现口腔黏膜、腮腺等不良反应,经处理后可完成治疗。结论:调强放射治疗和同步放化疗是治疗复发性鼻咽癌的一种可行、有效的方法。Objective：To investigate the effects and side effects of chemoradiotherapy with intensity modulated radiotherapy（IMRT） in the relapse Nasopharyngeal carcinoma.Methods：Total of 30 patients with relapse nasopharyngeal carcinoma were irradiated by IMRT technique.And also treated with chemoradiotherapy.Results：Of 30 patients,CR,PR,NC were 53.33%,23.33%,23.33%,respectively.The 1-year survival rates was 93.33%,the 1-year Local-regional control rate was 83.33%,the 1-year distant metastasis-free survival rate was 18.5%.Conclusion：Chemoradiotherapy plus IMRT is effective and well—tolerated for the treatment of relapse NPC.

关 键 词：调强放疗 化疗 鼻咽癌 

分 类 号：R739.62[医药卫生—肿瘤]