136例急性脑梗死血瘀证与Hs-CRP血脂四项的相关性研究  

Association between Changes of MMP-9、TIMP-1 Content and Blood Stasis Syndrome in Patients with Acute Cerebral infarction

作　　者：李林森[1,2] 田金洲[1] 蔡艺灵[3] 时晶[2] 邢亚楠[2] 孙文军[2] 

机构地区：[1]中央民族大学中国少数民族传统医学研究院,北京100081 [2]北京中医药大学东直门医院老年病科,北京100700 [3]中国人民解放军第306医院神经内科,北京100101

出　　处：《辽宁中医杂志》2010年第9期1636-1638,共3页Liaoning Journal of Traditional Chinese Medicine

基　　金：国家重点基础研究发展计划(973计划)资助项目(2003CB517104)

摘　　要：目的:探讨急性脑梗死患者血清HS-CRP、TC、TG、HDL、LDL变化与血瘀证的相关性。方法:对来源于中国人民解放军第306医院的136例脑梗死患者进行中医证候要素评分及血清HS-CRP、血脂四项测定。结果:血清HS-CRP、TC、TG、HDL、LDL比较,血瘀证组与非血瘀证组均无显著差异(P>0.05)。脑梗死血瘀证与血清HS-CRP、TC、TG、HDL、LDL无明显相关(P>0.05)。结论:急性脑梗死血瘀证与Hs-CRP、血脂四项无明显相关,本研究对于从细胞层面研究血瘀证的生物学基础有着重要意义。Objective：To investigate the blood stasis syndrome（ BSS） defined by traditional Chinese medicine in cerebral infarction and its correlations with changes of HS-CRP and blood-lipid content. Methods：All subjects comprised 136 patients with acute ischemis stroke,which were based on Diagnostic Criteria for Cerebral Vascular Diseases in 2005. Diagnosis for syndromes defined by traditional Chinese medicine were made according to Diagnostic Criteria for Stroke in 1994. Patients were examined for Hs-CRP and blood-lipid content in blood serum. Results：The levels of Hs-CRP and blood-lipid content in blood serum in patients with CI have BSS is no difference between patients with BSS and CI and those patients without BSS have CI（ P 0. 05）. There is no correlation between Hs-CRP and blood-lipid content in patients with CI have BSS（ P 0. 05）. Conclusion：There is no significantly correlation between Hs-CRP and blood-lipid content and BSS in patients with cerebral infarction. This preliminary study is of importance for study in biological basis of BSS by cell levels.

关 键 词：脑梗死 血瘀证 超敏C反应蛋白 血脂 

分 类 号：R743.33[医药卫生—神经病学与精神病学]