局部注射A型肉毒毒素对于脑卒中后下肢痉挛患者的影响  

Effects of Intramuscular Botulinum Toxin Type A Injection on Spasticity of Lower Limb after Stroke

作　　者：卢宇[1] 刘景隆[1] 李浩[1] 

机构地区：[1]哈尔滨市解放军第211医院康复理疗科,黑龙江哈尔滨市150080

出　　处：《中国康复理论与实践》2010年第9期811-812,共2页Chinese Journal of Rehabilitation Theory and Practice

摘　　要：目的评估局部注射A型肉毒毒素(BTX-A)对于脑卒中后下肢痉挛患者的痉挛程度、步行功能以及日常生活活动能力(ADL)的影响。方法 13例脑卒中后下肢痉挛的患者行局部注射BTX-A,分别在治疗前,治疗后1周、4周、8周和12周应用综合痉挛量表(CSS)、步长和步行速度、Barthel指数(BI)进行评估。结果治疗后下肢痉挛程度降低,BI升高(均P<0.05)。步长和步行速度虽有提高,但是无显著性差异(P>0.05)。所有改善均出现在治疗后1周,并持续至第12周。结论下肢局部注射BTX-A可以改善脑卒中后下肢痉挛患者的痉挛程度,提高ADL。Objective To investigate the effects of intramuscular Botulinum toxin type A（BTX-A）injection on spasticity of lower limb,walking and activities of daily living（ADL）after stroke.Methods13 patients with spasticity on lower limb were injected intramuscularly with BTX-A,and assessed with Composite Spasticity Scale（CSS）,step length and gait velocity,and Barthel index（BI）before and 1,4,8 and 12 weeks after treatment.ResultsThe scores of CSS and BI significantly improved after treatment（P〈0.05）.There was some improvement in step length and gait velocity,but not significant（P〈0.05）.All the improvement appeared 1 week after injection and lasted to the 12th week.ConclusionLocal intramuscular BTX-A injection can reduce the spasticity on lower limb and improve ADL.

关 键 词：脑卒中 痉挛 下肢 A型肉毒毒素 步行 日常生活活动能力 

分 类 号：R745.12[医药卫生—神经病学与精神病学]