非瓣膜病性房颤伴缺血性中风的二级预防  

A Secondary Prevention Study of Ischemic Stroke in Nonvalvular Atrial Fibrillation

作　　者：罗蔓[1] 谢瑞满[1] 全洪波[1] 

机构地区：[1]复旦大学附属中山医院老年病科,上海200032

出　　处：《中国临床医学》2010年第4期477-479,共3页Chinese Journal of Clinical Medicine

基　　金：上海市科技发展基金(编号:014L05)

摘　　要：目的:观察应用阿司匹林预防非瓣膜病性房颤伴缺血性中风患者复发的疗效。方法:选取89例非瓣膜病性房颤伴缺血性中风的患者,随机分为两组,其中阿司匹林组47例,丹参对照组42例,随访1年,观察阿司匹林及丹参片对其复发率病死率及其他血管事件发生率的影响。结果:对照组中风后1年的复发率高于阿司匹林组(P<0.05);对照组中风后1年的病死率与其他血管事件的发生率高于阿司匹林组,但差异无统计学意义(P>0.05)。结论:阿司匹林对非瓣膜病性房颤伴缺血性中风患者有预防复发的作用。Objective：To observe the influence of aspirin on the recurrence of ischemic stroke in nonvalvular atrial fibrillation（NVAF）.Methods： Eighty-nine patients with ischemic stroke in patient with NVAF in our hospital were included in this study.These patients were randomly divided into two groups,aspirin group for 47 cases and Salvia miltiorrhiza group for 42 cases.Follow up lasted for one year.Recurrent stroke,death and other vascular events were documented.Results： Compared with control,the recurrent stroke rate in aspirin group was lower（P0.05）.On the other hand,although death rate and other vascular events rate in aspirin group were lower than in Salvia miltiorrhiza group,there was no significant difference（P0.05）.Conclusions： our results suggest the benefits of aspirin for secondary stroke prevention in patients with ischemic stroke in NVAF.

关 键 词：非瓣膜病性房颤 缺血性中风 复发 阿斯匹林 

分 类 号：R743.3[医药卫生—神经病学与精神病学]