颈动脉内膜中层厚度与脑梗死后认知功能障碍的关系探讨  

The Relationship between Cognitive Impairment in Patients with Cerebral Infaction and Carotid Intima-Medial Thickness

作　　者：吴卫文[1] 顾青[1] 张建华[1] 杨钱红[1] 陆丽霞[1] 

机构地区：[1]复旦大学附属中山医院青浦分院神经内科超声诊断室,上海201700

出　　处：《中国临床医学》2010年第4期489-490,共2页Chinese Journal of Clinical Medicine

摘　　要：目的:探讨脑梗死后认知功能障碍的发生与颈动脉内膜中层厚度之间的关系。方法:对105例急性动脉粥样硬化性脑梗死患者在发病3周后用蒙特利尔(MOCA)量表进行认知功能障碍的筛查,并测定其颈动脉内膜中层的厚度。结果:伴有认知功能障碍者的颈动脉内膜中层厚度(IMT)明显大于对照组;随着IMT的增厚,MOCA量表评分下降,在视空间与执行能力、注意、语言、延迟回忆评分则更低(P<0.01),两者之间呈负相关(r=-0.56,P<0.01)。结论:动脉粥样硬化性脑梗死后认知功能障碍的发生与颈动脉内膜中层厚度有关。Objective：To investigate the relationship between cognitive impairment in patients with cerebral infaction and carotid intima-media thickness.Methods： After three weeks in patients with acute cerebral infarction,105 patients were carried out The montreal cognitive assessment（MOCA）and measured for carotid intima-media thickness（IMT）.Results： The carotid intima-media thickness of patients with cognitive impairment was thicker than that of the control group.With IMT thickening,MOCA score decrease.The score of visual-spatial and execution ability,noticeability,language and delayed recall were significantly lower（P 0.01）.MOCA score was negatively correlated with carotid intima-media thickness.Conclusions： Cognitive impairment in patients with cerebral infaction is related to carotid intima-media thickness.

关 键 词：颈动脉内膜中层厚度 脑梗死 认知功能障碍 

分 类 号：R743.3[医药卫生—神经病学与精神病学]