溃疡性结肠炎的临床和内镜特点  

Clinical Analysis on the Application of Endoscopy in Ulcerative Colitis

作　　者：张文明[1] 沈俊[2] 

机构地区：[1]复旦大学附属肿瘤医院内镜科,上海200032 [2]复旦大学上海医学院肿瘤学系,上海200032

出　　处：《中国临床医学》2010年第4期515-516,共2页Chinese Journal of Clinical Medicine

摘　　要：目的：分析溃疡性结肠炎的临床特点、肠镜表现、病理和实验室检查结果,提高临床对溃疡性结肠炎的诊治水平。方法：回顾分析2000年1月—2008年6月确诊的129例溃疡性结肠炎患者的临床资料。结果：发病平均年龄43.04岁,41~50年龄段发病比例最高,男性多见。临床症状：腹痛、腹泻,粘液脓血便,里急后重。结肠镜表现：黏膜慢性炎症。病理：炎性细胞浸润,隐窝改变。实验室检查：血小板计数、红细胞沉降率显著高于正常对照组。结论：溃疡性结肠炎病变主要位于直肠和乙状结肠。血小板计数和红细胞沉降率有助于溃疡性结肠炎的分期分型。Objective：To analyze the characteristics,endoscopic manifestations,pathological and laboratory results of ulcerative colitis（UC） in order to enhance the diagnosis and treatment of the disease.Methods：A total of 129 cases from Jan.2001 to Jun.2008 were analyzed retrospectively in terms of clinical symptoms,endoscopic manifestation,laboratory test and pathological studies.Results： The highest incidence was in 41 to 60 years old patients.Male was more common than female.The main clinical characteristics were diarrhea and abdominal pain.The main endoscopic manifestations features were mucosa chronic inflammations,multiple inflammatory cell infiltration and crypt architecture disorders.Lab studies including platelets（PLT） counts and erythrocyte sedimentation rate（ESR） were both higher than these of control group.Conclusions： Focus of the disease is situated in rectum and sigmoid colon.The level of PLT and ESR play important roles in the of the disease.

关 键 词：溃疡性结肠炎 结肠镜检查 临床分析 

分 类 号：R574.62[医药卫生—消化系统]