恶性梗阻性黄疸病人减黄术后低氮低热量肠外营养支持的临床研究  

The clinic research of hyponitrogenic and hypocaloric parenteral nutrition in patients with malignant obstructive jaundice after obstructive jaundice operation

作　　者：田虎[1] 付真[1] 

机构地区：[1]山东省千佛山医院普外中心肝胆外科,山东济南250014

出　　处：《肠外与肠内营养》2010年第5期260-263,共4页Parenteral & Enteral Nutrition

摘　　要：目的:探讨恶性梗阻性黄疸病人减黄术后低氮低热量肠外营养支持对机体代谢功能和免疫功能的影响。方法:将60例恶性梗阻性黄疸病人分为低氮低热量肠外营养组(A组)和普通肠外营养支持组(B组),每组30例。采用不同方法解除梗阻性黄疸2 d后行肠外营养支持5 d。观察肝功能、血脂、胆汁酸、营养指标和体液免疫、细胞免疫功能的变化。结果:全部病人胆道梗阻解除后均能耐受肠外营养支持,A组病人转氨酶、胆红素和胆汁酸水平明显下降,营养指标好转,血脂代谢改善,体液免疫和细胞免疫功能提高。结论:恶性梗阻性黄疸病人胆道梗阻解除后,肠外营养是一种安全的临床营养支持过渡手段,低氮低热量的代谢支持,对机体代谢功能和免疫功能恢复具有正相关性。Objective： To explore the effect of metabolic function and immune function of hyponitrogenic and hypocaloric parenteral nutrition in patients with malignant obstructive jaundice after obstructive jaundice operation.Methods： 60 patients with malignant obstructive jaundice patients accepted different treatment methods to relieve obstructive jaundice.Hyponitrogenic and hypocaloric parenteral nutrition（A group） or general parenteral nutrition（B group） was supported respectively.The changes of liver function,blood lipid,nutritional,index and immunity were observed,cellular immunity.Results： All patients after treatment were able to tolerate parenteral nutrition support.In A group,nutritional index of patients were improved,the levels of liver enzyms,bilirubin and bile acid were decreased obviously,humoral and cellular immunity indicators were improved,and blood lipid metabolism tended to normal range.Conclusion： Parenteral nutrition is safe after jaundice treatment for the patients with malignant obstructive jaundice.Hyponitrogenic and hypocaloric parenteral nutrition can effectively improve the nutritional status,metabolic function and immune function.

关 键 词：梗阻性黄疸 肠外营养 代谢功能 免疫功能 

分 类 号：R575[医药卫生—消化系统] R459.3[医药卫生—内科学]