以尼罗红为探针对新型两亲性树枝形聚合物微环境的研究  

Investigation of the Microenvironment of Novel Amphiphilic Dendrimers with Nile Red as a Probe

作　　者：袁钊[1,2] 曾毅[1] 陈金平[1] 李迎迎[1] 韩永滨[1] 李嫕[1] 

机构地区：[1]中国科学院理化技术研究所光化学转换与功能材料重点实验室,北京100190 [2]中国科学院研究生院,北京100049

出　　处：《影像科学与光化学》2010年第5期343-353,共11页Imaging Science and Photochemistry

基　　金：国家自然科学基金资助项目(20772134;20733007);国家重点基础研究发展规划项目(2007CB808004)

摘　　要：本工作合成了一系列外围以三缩四乙二醇单甲醚修饰的烷基芳醚骨架两亲性树枝形聚合物Gn(n=0—3),化合物通过了1H-NMR,IR和MALDI-TOF-MS的表征.利用吸收光谱,稳态和时间分辨荧光光谱研究了水溶液中Gn对尼罗红分子的增溶作用以及Gn内部微环境的极性.研究结果表明,高代数树枝形聚合物Gn对尼罗红具有更好的增溶效果.1—3代树枝形聚合物Gn内部疏水孔腔微环境极性随代数增加而逐渐降低,G1和G2树枝形聚合物具有相似的微环境极性,而由于构象的变化使G3具有更加疏水的微环境.Amphiphilic poly （alkyl aryl ether） dendrimers with tetraethylene glycol monomethyl ether at their periphery（Gn, n=0-3）, were synthesized by a convergent growth methodology and their structures were characterized by ^1H NMR, IR and mass spectroscopy （MALDI- TOF）. The microenvironment of these dendrimers was studied by using Nile Red as a fluorescence probe. The absorption spectra of Nile Red in water and Gn aqueous solutions indicate that the solubility of Nile Red increases dramatically with the increase of dendrimer generation. The steady state and time resolved fluorescence studies reveal that the microenvironrnent polarity of Gn（n=1-3） decreases with the increase of dendrimer generation. G1 and G2 dendrimers have similar microenvironment polarity, while G3 has a more hydrophobic inner cavity due to its globular structure.

关 键 词：树枝形聚合物 微环境极性 荧光光谱 尼罗红 

分 类 号：O631.3[理学—高分子化学]