高压氧、血液光量子疗法治疗急性缺血性卒中  

Hyperbaric Oxygen, Ultraviolet Blood Irradiation and Oxygenation in the Treatment of Acute Ischemic Stroke

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作  者:谈跃[1] 郭昆华[1] 朱榆红[1] 保明芳[1] 韩剑红[1] 

机构地区:[1]昆明医学院第二附属医院神经内科,昆明650101

出  处:《昆明医学院学报》1999年第2期14-18,共5页Journal of Kunming Medical College

基  金:云南省应用基础研究基金

摘  要: 145 例一侧颈动脉系统缺血性卒中患者按随机方法分为常规药物治疗组50 例 ( 对照组、 C 组) , H B O 治疗组39 例, 因3 例在 H B O 治疗中发生毒副作用而中止治疗( H 组) , U B I O 治疗组56 例 ( U 组) . 除 H B O 治疗和 U B I O 治疗外, 患者均进行常规药物治疗. 采用神经功能缺损程度评分. Barthel 指数, M M S E, C E S- D 等指标分别在治疗前后进行评定. 结果表明: C 组、 H 组、 U 组的总有效率分别为70 % , 75 % ,946 % ; 显效率分别为30 % , 306 % , 804 % ; U 组明显优于 C 组和 H 组 ( P< 0001) , 认知功能的改善( M M S E 评分) C 组不明显, U 组较治疗前改善 ( P< 005) , H 组最为明显, 优于 C 组( P< 005) , 情感障碍改善情况( C E S- D 评分) 与认知功能改善情况相一致. A D L 能力的恢复以 U B I O 治疗组最好. 并探讨了两种治疗方法的利弊关系, 治疗作用和影响临床疗效的因素.Patients with the onset of neurological deficits due to ischemic cerebral infarctio in the brain region perfused by one carotid artery were randomized to receive either treatment of hyperbaric oxygen (HBO) or ultraviolet blood irradiation and oxygenation (UBIO). A control group treated with drugs was set up. The results suggested that the short-term effective rates in HBO, UBIO, and control groups were 75%, 94.6%, 70% respectively. Marked rates were 30.6%, 80.4%, 30% respectively. The improvement of neurological deficits of the UBIO group was significantly better than that of the HBO group and the control group ( P <0.05). The mean score of cognition in the HBO group was significantly higher on the MMSE than that of the UBIO group and the control group ( P <0.05). Improvement of mood disorder was the same as that of cognition. The most significant improvement on ADL was observed in UBIO group. It is suggested that HBO might improve psychological outcome, and UBIO might improve neurological outcome after stroke.

关 键 词:脑缺血 高压氧疗法 光量子疗法 

分 类 号:R743.310.5[医药卫生—神经病学与精神病学]

 

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