结肠癌根治术的远期疗效分析  

Long-term outcome and prognostic factors of patients with colon cancer after radical resection

作　　者：王越[1] 葛春林[2] 沈春健[1] 王晓宇[1] 罗蓟[2] 

机构地区：[1]沈阳医学院沈洲医院外科,辽宁沈阳110002 [2]中国医科大学附属第一医院普通外科教研室,辽宁沈阳110001

出　　处：《中国现代医学杂志》2010年第16期2508-2510,共3页China Journal of Modern Medicine

摘　　要：目的探讨结肠癌根治术的远期效果和影响手术疗效的相关因素。方法回顾性分析了有完整临床资料并获得随访的241例结肠癌患者的临床特点、病理特征,并进行了预后多因素回归分析。结果结肠癌患者总的1,3,5生存率为82.9%,61.3%和56.7%。单因素分析显示,其预后与肿瘤组织类型、Dukes’分期、瘤细胞分化程度、淋巴结转移、远处转移均有相关性。应用Cox比例危险回归模型分析显示,肿瘤细胞分化程度和淋巴结转移是影响结肠癌患者预后的独立因素。结论结肠癌根治术后远期疗效与肿瘤细胞分化程度和淋巴结转移有关。【Objective】To investigate the long-term effect of colon cancer after radical operation and its impact on prognosis.【Methods】The clinical data of 241 colon cancer patients with clinical features,pathological features were retrospectively analyzed and make a multivariate analysis of prognosis was made.【Results】The overall 1-,3and 5-year survival rate of patients with colon cancer was 82.9%,61.3% and 56.7% respectively.Univariate analysis showed that tumor type,Dukes＇ stage,histological differentiation,lymph node metastasis,distant metastasis are relevant to long-term effect of colon cancer.Cox multivariate analysis shows that histological differentiation and lymph node metastasis were two independent prognostic factors.【Conclusion】The long-term effects of colon cancer after radical operation are histological differentiation and lymph node metastasis.

关 键 词：结肠肿瘤 根治术 回归分析 

分 类 号：R735.35[医药卫生—肿瘤]