经纤维支气管镜安置气道支架治疗恶性气道狭窄的临床分析  

Clinical Analysis on the Risks and Benefits of Tracheobronchial Stents in Patients with Malignant Airway Stenosis

作　　者：包郁[1] 王惬[1] 黄洁[1] 

机构地区：[1]四川省肿瘤医院,四川成都610041

出　　处：《中国呼吸与危重监护杂志》2010年第5期517-519,共3页Chinese Journal of Respiratory and Critical Care Medicine

摘　　要：目的了解恶性气道狭窄患者经纤维支气管镜安置气管支气管支架的中短期疗效及其并发症。方法对2006年1月至2008年5月安置气管支气管支架的恶性气道狭窄患者随访6个月,了解有效率、合并症及再安置率。结果 55例恶性气道狭窄患者共安置61个气管支气管支架,术中无患者死亡。即期有效率为100%,短期(<30 d)有效率为94.5%,6个月存活率为32.7%。并发症包括肿瘤通过支架向内生长、肉芽组织过多、支架移位以及再狭窄。短期发生并发症2例,中期发生并发症12例。结论对手术不能切除的恶性中央气道狭窄患者使用气管支气管支架置入短期疗效显著,能够迅速缓解症状,安全性较好,并发症主要发生于30 d之后。Objective To identify the short（30 days） and intermediate（30 days to 6 months） benefits and risks of tracheobronchial stents in patients with malignant airway stenosis.Methods 55 cases with malignant airway disease who underwent tracheobronchial stents placement from January 2006 to May 2008 were followed up for 6 months.The efficacy rate,complication rate,reintervention rate,and survival were analyzed.Results There were 61 self-expanding metal stents placed in 55 patients with malignant disease,with no intraoperative mortality.The immediate efficacy rate was 100%,the short-term（30 days） efficacy rate was 94.5%,and the survival rate in 6 months was 32.7%.The complications included tumor ingrowth,excessive granulation tissue,stent migration,and restenosis.A total of 14 cases of complications were observed,in which two occurred during the short-term period（30 days） and the remaining complications occurred after 30 days.Conclusions Tracheobronchial stents can improve symptoms immediately for the patients with unresectable malignant central airway obstruction with fairly safety.The benefit of airway stents is particularly seen in the short-term period and the complications occur mainly after 30 days.

关 键 词：肺癌 气道狭窄 支架 

分 类 号：R730.5[医药卫生—肿瘤]