Estimation of Probability of Unprotected Heterosexual Vaginal Transmission of HIV-1 from Clients to Female Sex Workers in Kaiyuan,Yunnan Province, China  

作　　者：WEN-JUAN MA JUN-JIE WANG KATHLEEN-H. REILLY AI-MEI BI GUO-WEI DING KUMI SMITH NING WANG 

机构地区：[1]School of Public Health, Peking Union Medical College, Tsinghua University, Beijing 100730, China [2]National Center for AIDS/STD Control and Prevention, Beijing 102206, China [3]Tulane University Health Sciences Center, School of Public Health and Tropical Medicine, New Orleans, LA, USA [4]Kaiyuan Center for Disease Control and Prevention, Kaiyuan 661600, Yunnan, China [5]University of North Carolina at Chapel Hill Chapel Hill NC, USA

出　　处：《Biomedical and Environmental Sciences》2010年第4期287-292,共6页生物医学与环境科学（英文版）

基　　金：supported by the mega-projects of national science research for the 11th Five-Year Plan of China (2008ZX10001-003)

摘　　要：Objective To estimate the probability of unprotected heterosexual vaginal transmission of HIV-1 from clients to Female Sex Workers （FSWs） in Kaiyuan County, Yunnan province, China, and analyze factors which impact the transmission probability. Methods An open cohort research of FSWs in Kaiyuan was created from surveys conducted in April 2008, October 2008, and April 2009. Two cross-sectional surveys of local clients were also carried out in May 2008 and November 2008. A model was developed to estimate the probability of unprotected heterosexual vaginal transmission of HIV-1 from clients to FSWs. Results The transmission probability from clients to FSWs was estimated as 0.0023 [95% CI 0.0014-0.0032] per unprotected heterosexual act. Conclusion The transmission probability among this group engaging in commercial sex in Yunnan province differs from that found in studies from other countries, and future studies should estimate the influence factors of HIV-1 transmission probability, such as stage of HIV infection, co-morbid sexually transmitted infections （STIs）.Objective To estimate the probability of unprotected heterosexual vaginal transmission of HIV-1 from clients to Female Sex Workers （FSWs） in Kaiyuan County, Yunnan province, China, and analyze factors which impact the transmission probability. Methods An open cohort research of FSWs in Kaiyuan was created from surveys conducted in April 2008, October 2008, and April 2009. Two cross-sectional surveys of local clients were also carried out in May 2008 and November 2008. A model was developed to estimate the probability of unprotected heterosexual vaginal transmission of HIV-1 from clients to FSWs. Results The transmission probability from clients to FSWs was estimated as 0.0023 [95% CI 0.0014-0.0032] per unprotected heterosexual act. Conclusion The transmission probability among this group engaging in commercial sex in Yunnan province differs from that found in studies from other countries, and future studies should estimate the influence factors of HIV-1 transmission probability, such as stage of HIV infection, co-morbid sexually transmitted infections （STIs）.

关 键 词：Transmission Probability HIV/AIDS Model FSW Clients 

分 类 号：S858.235.3[农业科学—临床兽医学] TU723.3[农业科学—兽医学]