儿童典型与不典型下丘脑错构瘤的MRI诊断  

MR Imaging Findings of Typical and Atypical Hypothalamic Hamartomas

作　　者：周俊霖[1] 李玉华[2] 李士建[2] 

机构地区：[1]江西省儿童医院放射科,330006 [2]上海交通大学医学院附属新华医院放射科,200092

出　　处：《临床放射学杂志》2010年第9期1229-1232,共4页Journal of Clinical Radiology

摘　　要：目的研究典型与不典型下丘脑错构瘤的MRI表现及临床特点,从而进一步提高对该病的认识。资料与方法分析经临床及MRI共同诊断的10例下丘脑错构瘤的特征。结果典型MRI表现5例,T1WI上错构瘤均表现为均匀等信号团块,与脑皮质信号相似,T2WI上肿块呈稍高信号。肿瘤以广基底或带蒂与灰结节和乳头体相连,增强后肿瘤未见明显强化。不典型MRI表现5例,肿瘤体积较大,合并坏死囊变,肿瘤可位于鞍背区或视交叉上方,增强后肿瘤实质部分未见明显强化。结论当患儿出现性早熟和(或)痴笑样癫痫为主的临床表现时,MRI显示下丘脑附近区域结节或肿块时,无论是否为典型下丘脑错构瘤MRI表现,若增强后肿瘤实质部分未见明显强化时,均应首先考虑本病。Objective To study the clinical and MRI findings of typical and atypical hypothalamic hamartoma,so as to improve the diagnosis.Materials and Methods The clinical and MRI data of 10 patients with hypothalamic hamartoma were analyzed.The patients underwent MRI plain and enhancement scan.Results On plain MRI images,the typical hypothalamic hamartomas（n=5） showed as isointense masses on T1WI and slight hyperintensity on T2WI without enhancement on contrast MRI images.The hypothalamic hamartomas connected to gray tubercle and mamillary body with wide base or pedicle.Atypical hypothalamic hamartomas（n=5）referred to giant hamartomas with necrosis or tumor located in atypical position.Conclusion Hypothalamic hamartoma should be considered firstly when patients have the symptom of gelastic epilepsy and/or precocious puberty,as well as non-enhanced nodules or masses located in the suprasella and hypothalamic regions.

关 键 词：下丘脑错构瘤 性早熟 磁共振成像 

分 类 号：R739.4[医药卫生—肿瘤]